67735-51-7

Basic information

• Product Name: N-methyl-N-phenylfuran-2-carboxamide
• Synonyms: 2-furancarboxamide, N-methyl-N-phenyl-; N-Methyl-N-phenyl-2-furamide
• CAS NO: 67735-51-7
• Molecular Formula: C₁₂H₁₁NO₂
• Molecular Weight: 201.2212
• Mol File: 67735-51-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 318.5°C at 760 mmHg
• Flash Point: 146.4°C
• Density: 1.186g/cm³
• Vapor Pressure: 0.000361mmHg at 25°C
• Refractive Index: 1.597
• CAS DataBase Reference: N-methyl-N-phenylfuran-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-N-phenylfuran-2-carboxamide(67735-51-7)
• EPA Substance Registry System: N-methyl-N-phenylfuran-2-carboxamide(67735-51-7)

Safety Data

• Hazardous Substances Data: 67735-51-7(Hazardous Substances Data)

Upstream product

• 527-69-5 2-furancarbonyl chloride 
• 100-61-8 N-methylaniline 
• 98-01-1 furfural 
• 121-69-7 N,N-dimethyl-aniline 
• 611-13-2 2-furoic acid methyl ester 
• 63633-79-4 N-(furan-2-carbonyl) saccharin 

Downstream Products

• 20895-16-3 1-(2-Furanyl)-3-methyl-1-butanone 
• 17572-16-6 furan-2-carbothioic acid-(N-methyl-anilide) 
• 1982-62-3 N-(p-tolyl)furan-2-carboxamide 

Relevant articles and documents

Nickel-Catalyzed Oxidative Transamidation of Tertiary Aromatic Amines with N -Acylsaccharins

The use of tertiary amines as surrogates for secondary amines has prominent advantages in terms of stabilization and ease of handling. A Ni-catalyzed transamidation of N -acylsaccharins with tertiary aromatic amines is reported. By using tert -butyl hydroperoxide as the terminal oxidant, this reaction permits selective cleavage of the C(sp 3)-N bonds of unsymmetrical tertiary aromatic amines depending on the sizes of the alkyl substituents.

Direct Alkoxycarbonylation of Heteroarenes via Cu-Mediated Trichloromethylation and in Situ Alcoholysis

We report an efficient approach for direct alkoxycarbonylation of furans as well as other heteroarenes via a one-step copper-mediated reaction of three components (i.e., heteroarene, alcohol, and CHCl3). The copper additive was confirmed to simultaneously promote the reaction in three pathways: oxidant cracking, single electron transfer, and alcoholysis. By means of this protocol, various functionalized furancarboxylates and other heteroarenecarboxylates were facilely obtained in moderate to good yields.

Iron-Catalyzed Oxidative Decarbonylative α-Alkylation of Acyl-Substituted Furans with Aliphatic Aldehydes as the Alkylating Agents

A protocol for FeCl2-catalyzed oxidative decarbonylative α-alkylation of acyl furans using alkyl aldehydes as the alkylating agents has been developed. This protocol affords α-alkyl-α-acylfurans in moderate to good yields in a practical and sustainable fa