67764-23-2

Basic information

• Product Name: 3,3-DIMETHYL-2-BUTYLMETHANESULPHONATE
• Synonyms: 3,3-DIMETHYL-2-BUTYLMETHANESULPHONATE
• CAS NO: 67764-23-2
• Molecular Formula: C₇H₁₆O₃S
• Molecular Weight: 180.27
• Mol File: 67764-23-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 256.9°C at 760 mmHg
• Flash Point: 109.2°C
• Appearance: /
• Density: 1.048g/cm³
• Vapor Pressure: 0.0241mmHg at 25°C
• Refractive Index: 1.436
• CAS DataBase Reference: 3,3-DIMETHYL-2-BUTYLMETHANESULPHONATE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-DIMETHYL-2-BUTYLMETHANESULPHONATE(67764-23-2)
• EPA Substance Registry System: 3,3-DIMETHYL-2-BUTYLMETHANESULPHONATE(67764-23-2)

Safety Data

• Hazardous Substances Data: 67764-23-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H16O3S/c1-6(7(2,3)4)10-11(5,8)9/h6H,1-5H3

Upstream product

• 464-07-3 3,3-dimethyl-2-butanol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 75-75-2 methanesulfonic acid 
• 464-07-3 3,3-dimethyl-2-butanol 

Relevant articles and documents

General, robust, and stereocomplementary preparation of β-ketoester enol tosylates as cross-coupling partners utilizing TsCl-N-methylimidazole agents

(Chemical Equation Presented) We have developed a general, robust, and cost-effective method for the (E)- or (Z)-stereocomplementary enol tosylation of β-ketoesters using TsCl-N-methylimidazole (NMI)-Et3N or LiOH. TsCl coupled with NMI formed a

Practical and efficient methods for sulfonylation of alcohols using Ts(Ms)Cl/Et3N and catalytic Me3N · HCl as combined base: Promising alternative to traditional pyridine

Several alcohols were smoothly and practically tosylated by two methods A and B. Method A uses the TsCl/Et3N (1.5 - 2.5 equiv)/cat. Me3N · HCl (0.1 - 1.0 equiv) reagent. Compared with the traditional Py-solvent method, the method A has merits of its much higher reaction rate, operational simplicity, economy in the use of the amine, and circumvention of the undesirable side reaction from R-OTs to R-CL. Method B uses TsCl/KOH [or Ca(OH)2]/cat. Et3N (0.1 equiv)/cat. Me3N · HCl (0.1 equiv) as the reagent, which will be suited for practical and large scale production for primary alcohols. On both methods A and B, a clear joint action of Et3N and Me3N · HCl catalysts was observed. 1H NMR measurements support the proposed mechanism of the catalytic cycle. Related methanesulfonylation using Et3N and cat. Me3N · HCl in toluene solvent also successfully proceeded, wherein the clear joint action was also observed.