678140-94-8

Basic information

• Product Name: Pyridine, 3-(diphenylphosphinyl)-
• CAS NO: 678140-94-8
• Molecular Formula: C17H14NOP
• Molecular Weight: 279.278
• Mol File: 678140-94-8.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Pyridine, 3-(diphenylphosphinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 3-(diphenylphosphinyl)-(678140-94-8)
• EPA Substance Registry System: Pyridine, 3-(diphenylphosphinyl)-(678140-94-8)

Safety Data

• Hazardous Substances Data: 678140-94-8(Hazardous Substances Data)

Upstream product

• 372-47-4 3-Fluoropyridine 
• 4559-70-0 Diphenylphosphine oxide 
• 67284-17-7 3-(tosyloxy)pyridine 
• 109-00-2 3-HYDROXYPYRIDINE 
• 1120-90-7 3-iodopyridine 
• 626-60-8 3-Chloropyridine 
• 3468-53-9 phenyl nicotinate 
• 107658-27-5 pyridin-3-yl trifluoromethanesulfonate 
• 1692-25-7 3-pyridylboronic acid 
• 626-55-1 3-Bromopyridine 
• 829-85-6 diphenylphosphane 

Relevant articles and documents

Preparation method of aromatic phosphine oxide compound

The invention relates to the field of organic synthesis, in particular to a preparation method of an aromatic phosphine oxide compound. The preparation method comprises the following steps: adding a P(O)-H compound, a fluoroaromatic compound and an alkali reagent into an organic solvent, conducting mixing, performing stirring for reaction, and carrying out cooling to obtain a mixed solution; and carrying out washing and extracting to obtain an organic phase, drying and distilling the organic phase, and performing column chromatography to obtain the aromatic phosphine oxide compound. The method is simple in reaction operation, only a proper amount of alkali needs to be added, special reaction conditions such as ligands, catalysts and additives are not needed, the reaction is simple and efficient, and good industrial application prospects are achieved.

NiCl 2as a Cheap and Efficient Precatalyst for the Coupling of Aryl Fluorosulfonate and Phosphite/Phosphine Oxide

Herein, NiCl 2is employed as a cheap precatalyst in the formation of C(sp 2)-P bond via cross-coupling reaction of phenol derivatives and phosphine oxides/phosphites. This catalytic system allows a variety of phenols with diverse functional groups to transform into phosphates with good yields. No additional additive is used in this reaction.

Visible-light-mediated semi-heterogeneous black TiO2/nickel dual catalytic C (sp2)-P bond formation toward aryl phosphonates

The combination of black TiO2 nanoparticles (NPs) with a nickel catalyst provides a low-cost, sustainable, and reusable alternative dual catalytic system to a homogeneous counterpart (noble metals). This black TiO2-photoredox/nickel dual catalytic system has efficiently driven C-P bond formation between aryl iodides and diarylphosphine oxides under visible light, providing good to excellent yields as well as tolerating a variety of functional groups. The practical application of this semi-heterogeneous protocol has been highlighted by a sunlight experiment, a gram-scale reaction, and a reusability test.