67817-30-5

Basic information

• Product Name: 1,3,4,6-TETRA-O-ACETYL-2-AZIDO-2-DEOXY-ALPHA-D-GALACTOPYRANOSE
• Synonyms: 1,3,4,6-TETRA-O-ACETYL-2-AZIDO-2-DEOXY-ALPHA-D-GALACTOPYRANOSE;2-AZIDO-2-DEOXY-1,3,4,6-TETRA-O-ACETYL-ALPHA-D-GALACTOPYRANOSE;Tetraacetylazidodeoxygalactopyranose;1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-a-D-galactopyranose;1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-galactopyranose ,98%;2-azido-2-deoxy-1,3,4,6-tetraacetateα-D-Galactopyranose
• CAS NO: 67817-30-5
• Molecular Formula: C₁₄H₁₉N₃O₉
• Molecular Weight: 373.32
• Product Categories: Biochemistry;Galactose;O-Substituted Sugars;Sugars
• Mol File: 67817-30-5.mol
• Article Data: 15

Chemical Properties

• Melting Point: 120.0 to 127.0 °C
• Appearance: /
• Storage Temp.: Refrigerator
• CAS DataBase Reference: 1,3,4,6-TETRA-O-ACETYL-2-AZIDO-2-DEOXY-ALPHA-D-GALACTOPYRANOSE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4,6-TETRA-O-ACETYL-2-AZIDO-2-DEOXY-ALPHA-D-GALACTOPYRANOSE(67817-30-5)
• EPA Substance Registry System: 1,3,4,6-TETRA-O-ACETYL-2-AZIDO-2-DEOXY-ALPHA-D-GALACTOPYRANOSE(67817-30-5)

Safety Data

• Hazardous Substances Data: 67817-30-5(Hazardous Substances Data)

Usage

General Description

1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-alpha-D-galactopyranose is a chemical compound with the molecular formula C14H19N3O8. It is a derivative of galactose, a simple sugar, and is modified with acetyl and azido groups. 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-alpha-D-galactopyranose is commonly used in the production of glycoconjugates, which are molecules composed of a carbohydrate (such as galactose) linked to another type of molecule. The azido group in 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-alpha-D-galactopyranose allows for further chemical modifications and coupling reactions, making it a useful tool in the study of complex carbohydrate structures and their biological functions. 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-alpha-D-galactopyranose also has potential applications in drug delivery and development.

InChI:InChI=1/C14H19N3O9/c1-6(18)22-5-10-12(23-7(2)19)13(24-8(3)20)11(16-17-15)14(26-10)25-9(4)21/h10-14H,5H2,1-4H3/t10-,11-,12+,13-,14+/m1/s1

Upstream product

• 68733-05-1 3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-D-galactopyranosyl nitrate 
• 10387-40-3 potassium thioacetate 
• 84278-00-2 1,3,4,6-tetra-O-acetyl-2-azido-2-deoxy-D-galactopyranose 
• 4098-06-0 triacetyl-D-galactal 
• 68733-06-2 3,4,6-tri-O-acetyl-2-azido-2-deoxy-β-D-galactopyranosyl nitrate 
• 68733-26-6 2-azido-2-deoxy-D-galactose 
• 108-24-7 acetic anhydride 
• 127-09-3 sodium acetate 
• 196398-25-1 3,4,6-tri-O-acetyl-2-azido-2-deoxy-α/β-D-galactopyranosyl nitrate 
• 68733-26-6 2-deoxy-2-azidogalactopyranose 
• 1772-03-8 D-(+)-galactosamine hydrochloride 
• 1666-13-3 diphenyl diselenide 

Downstream Products

• 67673-39-6 3,4,6-tri-O-acetyl-2-azido-2-deoxy-alpha-D-galactopyranosyl bromide 
• 83021-94-7 ethyl p-(3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-D-galactopyranosyloxy)cinnamate 
• 114643-47-9 (E)-3-[4-((2R,3R,4R,5R,6R)-3-Amino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-phenyl]-acrylic acid tert-butyl ester 
• 114643-46-8 (E)-3-[4-((2R,3R,4R,5R,6R)-4,5-Diacetoxy-6-acetoxymethyl-3-amino-tetrahydro-pyran-2-yloxy)-phenyl]-acrylic acid tert-butyl ester 
• 114643-37-7 p-(3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-D-galactopyranosyloxy)cinnamic acid 
• 114643-29-7 tert-butyl p-(3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-D-galactopyranosyloxy)cinnamate 
• 114656-12-1 N¹-p-(3,4,6-tri-O-acetyl-2-azido-2-deoxy-α-D-galactopyranosyloxy)cinnamoyl-N²,N³-di-tert-butoxycarbonylspermidine 
• 114643-54-8 N¹-cinnamoylspermidine dihydrochloride 
• 114643-42-4 N¹-p-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyloxy)cinnamoyl-N²,N³-di-tert-butoxycarbonylspermidine 
• 114643-39-9 p-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyloxy)cinnamic acid 
• 114643-38-8 tert-butyl p-(2-acetamido-3,4,6-tri-O-acetyl-α-D-galactopyranosyloxy)cinnamate 
• 1260181-53-0 phenyl 2-azido-2-deoxy-4,6-O-(p-methoxybenzylidene)-1-thio-α-D-galactopyranoside 
• 1260181-56-3 phenyl 3-O-acetyl-2-azido-4,6-O-benzylidene-2-deoxy-1-thio-α-D-galactopyranoside 
• 1260181-59-6 phenyl 3-O-acetyl-2-azido-2-deoxy-4,6-O-(p-methoxybenzylidene)-1-thio-α-D-galactopyranoside 

Relevant articles and documents

Immunological response from an entirely carbohydrate antigen: Design of synthetic vaccines based on Tn-PS A1 conjugates

(Figure Presented) An entirely carbohydrate-based immunogen consisting of a zwitterionic polysaccharide (ZPS) PS A1 and the well-known tumor antigen Tn has been designed, synthesized, and studied for immunological effects. The PS A1 motif was included to act as an MHCII elicitor for a T-cell-dependent immune response with increased immunogenicity against tumor-associated carbohydrate antigens, providing an alternative to carrier proteins. Through the use of C57BL/6 mice, it has been shown that chemical modification of PS A1 does not alter the recognition sequence responsible for an MHCII-mediated, T-cell-dependent immune response. The Tn-PS A1 conjugate construct confers specificity toward the Tn antigen alone, and specific carbohydrate immunoglobulins, namely, IgG3, are generated from intraperitoneal immunizations with or without adjuvant. The properties of the vaccine candidate are attributed to a site-specific linking strategy that incurs significant incorporation of Tn antigen.

Synthesis of trisaccharide repeating unit of fucosylated chondroitin sulfate

We described the chemical synthesis of a sulfated trisaccharide repeating unit of fucosylated chondroitin sulfate (FCS), which has significant anticoagulant activity. Well-functionalized monosaccharides were readily prepared, and highly efficient glycosyl

Synthetic and immunological studies on trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates

Therapeutic vaccines have been regarded as a very promising treatment modality against cancer. Tumor-associated MUC1 is a promising antigen for the design of antitumor vaccines. However, body's immune tolerance and low immunogenicity of MUC1 glycopeptides