67829-47-4Relevant articles and documents
Metal-free protocol for the synthesis of N-arylpyrrolidines catalyzed by hydrogen iodine
Hou, Tingting,Zhang, Chaofeng,Wang, Yehong,Liu, Zhenting,Zhang, Zhixin,Wang, Feng
, p. 56 - 59 (2017/03/09)
A metal-free and efficient approach to N-arylpyrrolidines from arylamines and cyclic ethers catalyzed by hydrogen iodine is described. In this protocol, no additive is added and a wide range of N-arylpyrrolidines are synthesized with up to 99% yield. Reaction mechanism involving iodine radical is proposed.