6786-41-0 Usage
General Description
Spiro[indoline-3,3'-pyrrolidin]-2-one is a chemical compound with a unique spirocyclic structure, consisting of a pyrrolidine ring fused with an indoline moiety. It is a heterocyclic compound with potential pharmacological activities, including anti-inflammatory, anti-tumor, and analgesic effects. spiro[indoline-3,3'-pyrrolidin]-2-one has been used as a core structure in the synthesis of various biologically active molecules, making it an important intermediate in medicinal chemistry research. Additionally, spiro[indoline-3,3'-pyrrolidin]-2-one has shown potential as a chiral building block for the development of enantioselective catalysts and ligands in asymmetric synthesis. Its diverse biological and synthetic applications make it a valuable target for chemical synthesis and medicinal chemistry studies.
Check Digit Verification of cas no
The CAS Registry Mumber 6786-41-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,8 and 6 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6786-41:
(6*6)+(5*7)+(4*8)+(3*6)+(2*4)+(1*1)=130
130 % 10 = 0
So 6786-41-0 is a valid CAS Registry Number.
6786-41-0Relevant articles and documents
Synthesis of (±)-coerulescine and a formal synthesis of (±)-horsfiline
Chang, Meng-Yang,Pai, Chun-Li,Kung, Yung-Hua
, p. 8463 - 8465 (2007/10/03)
A straightforward synthesis of (±)-coerulescine and (±)-horsfiline has been established from 3-formyl-3-phenylpyrrolidine employing 4-hydroxypiperidine as the starting material. There are two remarkable steps for the synthesis of (±)-coerulescine and (±)-horsfiline. One is the rapid access to produce 3-formyl-3-phenylpyrrolidine by Lewis acid-catalyzed rearrangement of 3,4-dihydroxy-4-phenylpiperidine. The other key step is an intramolecular electrophilic cyclization from 3-benzylcarbamoyl-3- phenylpyrrolidine to the 3,3-spirocyclic 2-oxindole ring skeleton.
