67913-13-7

Basic information

• Product Name: 2,5-Cyclohexadiene-1,4-dione, 2,3-dimethoxy-6-methyl-5-(2-propenyl)-
• CAS NO: 67913-13-7
• Molecular Formula: C12H14O4
• Molecular Weight: 222.241
• Mol File: 67913-13-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2,5-Cyclohexadiene-1,4-dione, 2,3-dimethoxy-6-methyl-5-(2-propenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Cyclohexadiene-1,4-dione, 2,3-dimethoxy-6-methyl-5-(2-propenyl)-(67913-13-7)
• EPA Substance Registry System: 2,5-Cyclohexadiene-1,4-dione, 2,3-dimethoxy-6-methyl-5-(2-propenyl)-(67913-13-7)

Safety Data

• Hazardous Substances Data: 67913-13-7(Hazardous Substances Data)

Usage

General Description

2,5-Cyclohexadiene-1,4-dione, 2,3-dimethoxy-6-methyl-5-(2-propenyl)-, commonly known as umbelliferone, is a chemical compound with a chemical formula C16H14O4. It is a natural product found in many plants and is commonly used in the synthesis of pharmaceuticals and dyes. Umbelliferone has antioxidant, anti-inflammatory, and antimicrobial properties, making it a valuable compound in the pharmaceutical and cosmetic industries. It is also used in the food industry as a flavoring agent and in the production of perfumes and fragrances. Additionally, umbelliferone has been studied for its potential anticancer and neuroprotective properties, making it a promising compound for future research and development.

Upstream product

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• 73875-27-1 2,3,4,5-tetramethoxy-6-methyl-1-bromobenzene 
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• 19676-64-3 2,3,4-trimethoxyphenol 
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• 13909-73-4 2',3',4'-trimethoxyacetophenone 
• 21450-56-6 1,2,3,4-tetramethoxybenzene 
• 605-94-7 2,3-Dimethoxy-5-methyl-1,4-benzoquinone 
• 152898-31-2 3-allyloxy-4,5-dimethoxytoluene 
• 124603-27-6 2,3-dimethoxy-4-(1-propenyl)-4-(2-propenyloxy)-2-cyclobuten-1-one 
• 71573-66-5 1‐allyl‐2,3,4,5‐tetramethoxy‐6‐methylbenzene 

Downstream Products

• 71573-66-5 1‐allyl‐2,3,4,5‐tetramethoxy‐6‐methylbenzene 
• 1431987-03-9 3-(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dienyl)propane-1,2-diyl dinitrate 
• 1431987-54-0 di-tert-butyl 2-allyl-5,6-dimethoxy-3-methyl-1,4-phenylene dicarbonate 
• 1431987-55-1 di-tert-butyl 2-(2,3-bis(nitrooxy)propyl)-5,6-dimethoxy-3-methyl-1,4-phenylene dicarbonate 

Relevant articles and documents

QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS

The present invention relates to nitric oxide donor compounds having a quinone based structure, to processes for their preparation and to their use in the treatment and/or prophylaxis of glaucoma and ocular hypertension.

QUINONE BASED NITRIC OXIDE DONATING COMPOUNDS

The present invention relates to nitric oxide donor compounds having a quinone based structure, to processes for their preparation and to their use in the treatment of pathological conditions where a deficit of NO plays an important role in their pathogenesis.

Synthesis of crown ethers related to ubiquinones

Crown ethers in which the two methoxy groups of ubiquinone-0 (2,3-dimethoxy-5-methyl-1,4-benzoquinone) are replaced by oligoethylene glycol bridges have been obtained in five straightforward steps in 35-40% overall yield from 5-methylpyrogallol. A Fremy salt oxidation of a phenolic precursor is used in the final step. The further elaboration of crown ether analogues of ubiquinone-2 was achieved by enol geranylation of cyclopentadiene adducts of the former quinones and subsequent retro-Diels-Alder reaction. The Claisen rearrangement of 2,2-dimethoxy-5-methylphenyl allyl ethers and related crown ethers affords ortho- and para-allyl-substituted phenols (3:1) that are oxidized to give bisnorubiquinone derivatives and their ortho-quinone isomers. All new compounds are characterized by high resolution NMR and mass spectrometry.