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68045-12-5

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68045-12-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 68045-12-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,0,4 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 68045-12:
(7*6)+(6*8)+(5*0)+(4*4)+(3*5)+(2*1)+(1*2)=125
125 % 10 = 5
So 68045-12-5 is a valid CAS Registry Number.

68045-12-5Upstream product

68045-12-5Downstream Products

68045-12-5Relevant articles and documents

Synthesis of cyclic adenosine 5′-diphosphate ribose analogues: A C2′ endo/syn "southern" ribose conformation underlies activity at the sea urchin cADPR receptor

Moreau, Christelle,Ashamu, Gloria A.,Bailey, Victoria C.,Galione, Antony,Guse, Andreas H.,Potter, Barry V. L.

, p. 278 - 290 (2011)

Novel 8-substituted base and sugar-modified analogues of the Ca 2+ mobilizing second messenger cyclic adenosine 5′-diphosphate ribose (cADPR) were synthesized using a chemoenzymatic approach and evaluated for activity in sea urchin egg homogenate (SUH) and in Jurkat T-lymphocytes; conformational analysis investigated by 1H NMR spectroscopy revealed that a C2′ endo/syn conformation of the "southern" ribose is crucial for agonist or antagonist activity at the SUH-, but not at the T cell-cADPR receptor.

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