68055-34-5

Basic information

• Product Name: N-benzyl-4-methylbenzenecarbothioamide
• Synonyms: benzenecarbothioamide, 4-methyl-N-(phenylmethyl)-; N-Benzyl-4-methylbenzenecarbothioamide
• CAS NO: 68055-34-5
• Molecular Formula: C₁₅H₁₅NS
• Molecular Weight: 241.3513
• Mol File: 68055-34-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 372.6°C at 760 mmHg
• Flash Point: 179.2°C
• Density: 1.124g/cm³
• Vapor Pressure: 9.5E-06mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: N-benzyl-4-methylbenzenecarbothioamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-4-methylbenzenecarbothioamide(68055-34-5)
• EPA Substance Registry System: N-benzyl-4-methylbenzenecarbothioamide(68055-34-5)

Safety Data

• Hazardous Substances Data: 68055-34-5(Hazardous Substances Data)

Upstream product

• 5436-83-9 N-benzyl-4-methylbenzamide 
• 100063-20-5 N-p-Thiotoluyl-succinimid 
• 100-46-9 benzylamine 
• 865077-50-5 (1H-benzo[d][1,2,3]triazol-1-yl)(p-tolyl)methanethione 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 99-94-5 p-Toluic acid 
• 681440-55-1 4-methylthiobenzoic acid O-(4-nitrophenyl) ester 
• 104-87-0 4-methyl-benzaldehyde 

Downstream Products

• 5436-83-9 N-benzyl-4-methylbenzamide 

Relevant articles and documents

A multipathway coupled domino strategy: I2-mediated oxidative thionation for direct synthesis of thiobenzamides from miscellaneous substrates

An efficient iodine-mediated multipathway coupled domino reaction has been developed for the synthesis of thiobenzamides from benzylamines, benzylamines/aldehydes, and N-alkyl benzylamines under the same reaction conditions. This approach combines two consecutive domino processes in one pot using iodine as the oxidant.

Benzotriazole-assisted thioacylation

Benzotriazole reagents for thioacylation (RCSBt), thiocarbamoylation (RR'NCSBt), aryl/alkoxy-thioacylation (ROCSBt), and aryl/alkylthiothioacylation (RSCSBt) are synthesized, and their utility is assessed by syntheses of representative heteroaryl thioureas 3a-g, thioamides 15a-s, thionoesters 16a-h, thiocarbamates 17a-e, dithiocarbamates 18a-d, thiocarbonates 19a-c, and dithiocarbonates 20a-c.