680610-54-2

Basic information

• Product Name: Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)-
• CAS NO: 680610-54-2
• Molecular Formula: C10H9F4NO2
• Molecular Weight: 251.181
• Mol File: 680610-54-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)-(680610-54-2)
• EPA Substance Registry System: Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)-(680610-54-2)

Safety Data

• Hazardous Substances Data: 680610-54-2(Hazardous Substances Data)

Upstream product

• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 115029-22-6 2-fluoro-3-(trifluoromethyl)benzoic acid 
• 208173-19-7 2-fluoro-3-trifluoromethylbenzoyl chloride 

Downstream Products

• 854778-39-5 [2-fluoro-3-(trifluoro-methyl)phenyl](3-methoxyphenyl)methanone 
• 1227290-31-4 3,4-dimethoxyphenyl[(2-fluoro-3-(trifluoromethyl)phenyl)]methanone 
• 680610-69-9 2,4-dimethoxyphenyl[(2-fluoro-3-(trifluoromethyl)phenyl)]methanone 
• 680611-18-1 3-(2,4-dimethoxyphenyl)-7-(trifluoromethyl)-1H-indazole 
• 1227290-32-5 3-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)-1H-indazole 
• 1173793-72-0 2-fluoro-[3-(trifluoromethyl)phenyl](1-methyl-1H-tetrazol-5-yl)methanone 
• 875795-91-8 (2-fluoro-3-(trifluoromethyl)phenyl)(4-fluorophenyl)methanone 
• 1085267-45-3 (2-fluoro-3-(trifluoromethyl)phenyl)(4-chlorophenyl)methanone 
• 908566-32-5 1-[2-fluoro-3-(trifluoromethyl)phenyl]-3-phenylpropan-1-one 
• 1026186-75-3 1-benzyl-3-(4-methoxy-phenyl)-7-trifluoromethyl-1H-indazole 
• 1027887-95-1 2-[3-(4-methoxy-phenyl)-7-trifluoromethyl-indazol-1-yl]-ethanol 
• 680611-14-7 3-(4-methoxy-phenyl)-7-trifluoromethyl-1H-indazole 
• 680610-53-1 (2-fluoro-3-trifluoromethyl-phenyl)-(4-methoxy-phenyl)-methanone 

Relevant articles and documents

TETRAZOLINONE COMPOUND AND USE THEREOF

The compound represented by formula (1): wherein R4 and R5 each represents a hydrogen atom, a halogen atom, or a C1-C3 alkyl group; R6 represents a C1-C4 alkyl group, a C3-C6 cycloalkyl group, or the like; R7, R8, and R9 each represents a hydrogen atom, a halogen atom, or the like; R10 represents a C1-C3 alkyl group, or the like; R13 represents a C1-C3 alkyl group, or the like; and Q represents a phenyl group, or the like; has an excellent control effect on pests.

Development of a selective modulator of aryl hydrocarbon (Ah) receptor activity that exhibits anti-inflammatory properties

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. However, the role of the AHR in normal physiology is still an area of intense investigation. For example, thi

Discovery and SAR of cinnolines/quinolines as liver X receptor (LXR) agonists with binding selectivity for LXRβ

A series of cinnolines/quinolines was prepared and it was found that 4-phenyl-cinnoline/quinolines with either a 2′,3′ or 2′,5′-disubstituted benzyloxy moiety or the 1-Me-7-indole methoxy moiety on the meta position of the 4-phenyl ring showed good binding selectivity for LXRβ over LXRα. The LXRβ binding selective modulators displayed good activity for inducing ABCA1 gene expression in J774 macrophage cell line and poor efficacy in the LXRα Gal4 functional assay. 26, 37 and 41 were examined for their ability to induce SREBP-1c gene expression in Huh-7 liver cell line and they were weak partial agonists.