68074-34-0

Basic information

• Product Name: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2',3'-O-(1-methylethylidene)-
• CAS NO: 68074-34-0
• Molecular Formula: C34H35N5O6
• Molecular Weight: 609.682
• Mol File: 68074-34-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2',3'-O-(1-methylethylidene)-(CAS DataBase Reference)
• NIST Chemistry Reference: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2',3'-O-(1-methylethylidene)-(68074-34-0)
• EPA Substance Registry System: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2',3'-O-(1-methylethylidene)-(68074-34-0)

Safety Data

• Hazardous Substances Data: 68074-34-0(Hazardous Substances Data)

Upstream product

• 103022-64-6 5'-acetyl-N⁶,N⁶-di-p-toluyl-2',3'-O-isopropylideneadenosine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 362-75-4 2',3'-isopropylidene adenosine 
• 51008-69-6 2',3'-O-isopropylidene-N⁶,N⁶,5'-O-tri-p-toluyladenosine 
• 15888-38-7 5'-acetyl-2',3'-isopropylideneadenosine 

Downstream Products

• 103062-68-6 N⁶,N⁶-di-p-toluyl-2',3'-O-isopropylideneadenosine 
• 93135-74-1 7,8-dihydro-N⁶,7-di-p-toluyl-2',3'-O-isopropylidene-8,5'-O-cycloadenosine 
• 192052-71-4 (9-{(3aR,4R,6R,6aR)-6-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-9H-purin-6-yl)-carbamic acid benzyl ester 
• 103022-63-5 5'-O-(4,4'-dimethoxytrityl)-N⁶,N⁶-di-p-toluyl-2',3'-O-isopropylideneadenosine 
• 192052-72-5 Boc-Glu(O^tBu)-Tyr[CO(CH₂)4CO-bzoc⁶A(=CMe₂)]-Leu-morpholine 
• 192052-70-3 Hexanedioic acid mono-[(3aR,4R,6R,6aR)-6-(6-benzyloxycarbonylamino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl] ester 
• 192052-69-0 N⁶-benzoyl-2',3'-isopropylidene adenosine 

Relevant articles and documents

Synthesis of Modified Tripeptides and Tetrapeptides as Potential Bisubstrate Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase

Thesynthesis of a series of bisubstrate inhibitors of the epiermal growth factor receptor protein kinase (EGF-R PTK) consisting of small peptides linked covalently to adenosine via appropriate triphosphate substitutes is described.Boc-Glu(O'Bu)-Tyr-Leu-OB

Acyl migration from N6 to N7 of a 2',3'-O-isopropylideneadenosine derivative accompained by cyclonucleoside formation

Reaction of 2',3'-O-isopropylideneadenosine (1) with p-NCC6H4COCl in 1:6 Et3N-CH2Cl2 afforded the cyanoimidazole nucleoside 8 (53percent) and the 8,5'-O-cycloadenosine derivative 7 (29percent).Treatment of N6,N6-di-p-toluyl-2',3'-O-isopropilideneadenosine (23) with ZnBr2 in p-dioxane resulted in acyl migration from N6 to N7 to give the cycloadenosine derivative 4.The coordination site of the zinc cation on the base moiety of adenosine derivatives was determined by 15N nmr spectra.