68097-99-4

Basic information

• Product Name: 4,6-bis(N-piperidinylmethyl)-2,5-dimethylphenol
• Synonyms: 4,6-bis(N-piperidinylmethyl)-2,5-dimethylphenol
• CAS NO: 68097-99-4
• Molecular Weight: 316.487
• Mol File: 68097-99-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4,6-bis(N-piperidinylmethyl)-2,5-dimethylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-bis(N-piperidinylmethyl)-2,5-dimethylphenol(68097-99-4)
• EPA Substance Registry System: 4,6-bis(N-piperidinylmethyl)-2,5-dimethylphenol(68097-99-4)

Safety Data

• Hazardous Substances Data: 68097-99-4(Hazardous Substances Data)

Upstream product

• 880-09-1 di(N-piperidinyl)methane 
• 95-87-4 2,5-Dimethylphenol 
• 3275-13-6 1-(ethoxymethyl)piperidine 
• 20276-55-5 N-methylenepiperidinium chloride 
• 110-89-4 piperidine 
• 50-00-0 formaldehyd 

Relevant articles and documents

The activation of aminals and aminol ethers by sulfur dioxide and their reactions with electron rich aromatic compounds

Reactions of bis(dialkylamino)methanes and ethoxydialkylaminomethanes with nucleophilic aromatic heterocycles in the presence of sulfur dioxide result in the formation of the expected Mannich bases in good yields. Reactions of phenols are similarly activated by sulfur dioxide which lead to improved regioselectivity: in particular the reactions of 2,5-dimethylphenol result in the formation of 2-dialkylaminomethyl-3,6-dimethylphenol whereas reaction occurs at the I-position using the classical procedures.