68099-19-4

Basic information

• Product Name: 2-Cyclohepten-1-ol, 1-phenyl-
• CAS NO: 68099-19-4
• Molecular Formula: C13H16O
• Molecular Weight: 188.269
• Mol File: 68099-19-4.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 2-Cyclohepten-1-ol, 1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohepten-1-ol, 1-phenyl-(68099-19-4)
• EPA Substance Registry System: 2-Cyclohepten-1-ol, 1-phenyl-(68099-19-4)

Safety Data

• Hazardous Substances Data: 68099-19-4(Hazardous Substances Data)

Upstream product

• 1121-66-0 2-Cyclohepten-1-one 
• 100-58-3 phenylmagnesium bromide 
• 108-86-1 bromobenzene 
• 79605-67-7 2-cycloheptenol 
• 591-51-5 phenyllithium 

Downstream Products

• 1206544-15-1 2-methyl-5-(3-phenylcyclohept-2-enyl)furan 
• 147068-27-7 3-phenyl-2-cyclohepten-1-one 
• 1234577-25-3 benzyl (RS)-(3-phenylcyclohept-2-en-1-yl)carbamate 
• 57293-43-3 1-phenyl-1,3-cycloheptadiene 

Relevant articles and documents

Palladium-Catalyzed Asymmetric Tandem Denitrogenative Heck/Tsuji-Trost of Benzotriazoles with 1,3-Dienes

The asymmetric denitrogenative cycloaddition has emerged as a powerful tool to build chiral aza-heterocyles. However, only one example of asymmetric denitrogenative cycloaddition of benzotriazole with unsaturated hydrocarbons has been explored so far, bec

Preparation of optically active cycloalkenes bearing all-carbon quaternary stereogenic centres: Via lipase-oxovanadium combo-catalysed dynamic kinetic resolution

In this study, a novel asymmetric synthesis of all-carbon quaternary stereogenic centres is developed by the connection of three prochiral or achiral components - conjugated enones, organometallic compounds and vinyl esters - at the C-1 position of the enones. This method involves three sequential steps: 1,2-nucleophilic addition of an organometallic compound to the enone, lipase-catalysed dynamic kinetic resolution (DKR) of the tert-allylic alcohol and the Ireland-Claisen rearrangement of the optically active allyl ester thus generated. This method features the effective use of acyl moieties installed by DKR for achieving high atom economy. The application of this method to the protective-group-free asymmetric total synthesis of (-)-crinane, a core structure of a class of natural alkaloids, has demonstrated that it can alter a known synthetic pathway of a racemate into an asymmetric synthesis of an optically pure molecule while reducing the total transformation steps and increasing the overall yield. With these advantages, this method is practical and attractive as a new environmentally benign protocol.

Palladium-catalyzed oxidative rearrangement of tertiary allylic alcohols to enones with oxygen in aqueous solvent

A one-pot procedure for Pd(TFA)2-catalyzed 1,3-isomerization of tertiary allylic alcohols to secondary allylic alcohols followed by a Pd(TFA)2/neocuproine-catalyzed oxidative reaction to β-disubstituted-α,β-unsaturated kenones was developed. (Chemical Equation Presented).