681151-76-8

Basic information

• Product Name: N-(2-amino-ethyl)-O-(4-chloro-benzyl)-hydroxylamine
• CAS NO: 681151-76-8
• Molecular Weight: 200.668
• Mol File: 681151-76-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-amino-ethyl)-O-(4-chloro-benzyl)-hydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-amino-ethyl)-O-(4-chloro-benzyl)-hydroxylamine(681151-76-8)
• EPA Substance Registry System: N-(2-amino-ethyl)-O-(4-chloro-benzyl)-hydroxylamine(681151-76-8)

Safety Data

• Hazardous Substances Data: 681151-76-8(Hazardous Substances Data)

Upstream product

• 681145-54-0 2-[2-(4-chloro-benzyloxyamino)-ethyl]-isoindole-1,3-dione 
• 39030-46-1 2-((4-chlorobenzyl)oxy)isoindoline-1,3-dione 
• 5555-51-1 (4-chlorobenzyl)oxyamine 
• 873-76-7 para-Chlorobenzyl alcohol 

Downstream Products

• 681153-23-1 1-(4-chloro-benzyloxy)-4,5-dihydro-1H-imidazole-2-thiol 

Relevant articles and documents

1-Benzyloxy-4,5-dihydro-1H-imidazol-2-yl-amines, a novel class of NR1/2B subtype selective NMDA receptor antagonists

Screening of the Roche compound depository led to the identification of (1-benzyloxy-4,5-dihydro-1H-imidazol-2-yl)-butyl amine 4, a structurally novel NR1/2B subtype selective NMDA receptor antagonist. The structure-activity relationships developed in this series resulted in the discovery of a novel class of potent and selective NMDA receptor blockers displaying activity in vivo.