681429-25-4

Basic information

• Product Name: [Pt(SeC(NC₆H₅)NC₆H₅)(P(C₆H₅)3)2]
• Synonyms: [Pt(SeC(NC₆H₅)NC₆H₅)(P(C₆H₅)3)2]
• CAS NO: 681429-25-4
• Molecular Weight: 992.858
• Mol File: 681429-25-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [Pt(SeC(NC₆H₅)NC₆H₅)(P(C₆H₅)3)2](CAS DataBase Reference)
• NIST Chemistry Reference: [Pt(SeC(NC₆H₅)NC₆H₅)(P(C₆H₅)3)2](681429-25-4)
• EPA Substance Registry System: [Pt(SeC(NC₆H₅)NC₆H₅)(P(C₆H₅)3)2](681429-25-4)

Safety Data

• Hazardous Substances Data: 681429-25-4(Hazardous Substances Data)

Upstream product

• 603-35-0 triphenylphosphine 
• 10199-34-5 cis-dichlorobis(triphenylphosphine)platinum(II) 
• 16519-43-0 1,3-diphenyl-selenourea 

Relevant articles and documents

Synthesis and crystal structure of the first complex containing a chelating selenourea dianion ligand

Reaction of N,N′-diphenylselenourea, PhNHC(Se)NHPh, with cis-[PtCl2(PPh3)2] and triethylamine in hot methanol gives the first example of a selenourea dianion complex, [Pt{SeC(=NPh)NPh}(PPh3)2] isolated as a yellow solid in high yield. The structure of the complex was determined by X-ray crystallography and found to be similar to the related thiourea dianion complex [Pt{SC(=NPh)NPh}(PPh3)2], with a Pt-Se-C-N four-membered ring. The antitumour activity (P388 murine leukaemia cells) of the selenourea dianion complex was determined, together with a small selection of related platinum(II)-thiourea dianion complexes (prepared by an analogous method) for comparison. The complex [Pt{SC(=NMe)NMe}(PPh3)2] showed high activity [IC50 1.0 μM], with the other complexes showing moderate to low activity.