681492-12-6

Basic information

• Product Name: 4-[4-(2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazol-2-ylmethoxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-[4-(2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazol-2-ylmethoxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester
• CAS NO: 681492-12-6
• Molecular Weight: 459.502
• Mol File: 681492-12-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[4-(2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazol-2-ylmethoxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-(2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazol-2-ylmethoxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester(681492-12-6)
• EPA Substance Registry System: 4-[4-(2-methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazol-2-ylmethoxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester(681492-12-6)

Safety Data

• Hazardous Substances Data: 681492-12-6(Hazardous Substances Data)

Upstream product

• 1001314-80-2 2‐bromo‐1‐((2‐methyloxiran‐2‐yl)methyl)‐4‐nitro‐1H‐imidazole 
• 158985-25-2 tert-butyl 4-(4-hydroxyphenyl)piperazine-1-carboxylate 

Downstream Products

• 1001315-30-5 2-methyl-6-nitro-2-(4-piperazin-1-yl-phenoxymethyl)-2,3-dihydro-imidazo[2,1-b]oxazole 

Relevant articles and documents

NITROHETEROARYL-CONTAINING RIFAMYCIN DERIVATIVES

Substituted rifamycin derivatives in which a nitroimidazole, nitrothiazole or nitrofuran pharmacophore is covalently bonded to a rifamycin, methods of using the rifamycin derivatives, and pharmaceutical compositions containing the rifamycin derivatives are disclosed. Methods of synthesizing these substituted rifamycin derivatives are also disclosed. The rifamycin derivatives possess antibacterial activity, and are effective against a number of human and veterinary pathogens in the treatment of bacterial diseases.