68160-34-9

Basic information

• Product Name: 2,3-dimethoxy-5-[(4-methoxyphenyl)sulfanyl]cyclohexa-2,5-diene-1,4-dione
• CAS NO: 68160-34-9
• Molecular Formula: C₁₅H₁₄O₅S
• Molecular Weight: 306.3337
• Mol File: 68160-34-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 500.2°C at 760 mmHg
• Flash Point: 258.4°C
• Density: 1.32g/cm³
• Vapor Pressure: 3.87E-10mmHg at 25°C
• Refractive Index: 1.598
• CAS DataBase Reference: 2,3-dimethoxy-5-[(4-methoxyphenyl)sulfanyl]cyclohexa-2,5-diene-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dimethoxy-5-[(4-methoxyphenyl)sulfanyl]cyclohexa-2,5-diene-1,4-dione(68160-34-9)
• EPA Substance Registry System: 2,3-dimethoxy-5-[(4-methoxyphenyl)sulfanyl]cyclohexa-2,5-diene-1,4-dione(68160-34-9)

Safety Data

• Hazardous Substances Data: 68160-34-9(Hazardous Substances Data)

Usage

General Description

2,3-dimethoxy-5-[(4-methoxyphenyl)sulfanyl]cyclohexa-2,5-diene-1,4-dione is a chemical compound with the molecular formula C15H16O5S. It consists of a cyclohexadienedione ring with two methoxy and one methoxyphenylsulfanyl groups attached. 2,3-dimethoxy-5-[(4-methoxyphenyl)sulfanyl]cyclohexa-2,5-diene-1,4-dione is a yellow crystalline solid and is commonly used in organic synthesis and medicinal chemistry. It has been studied for its potential biological activities and is of interest in the development of new pharmaceuticals.

Upstream product

• 696-63-9 4-Methoxybenzenethiol 
• 3117-02-0 2,3-dimethoxy-1,4-benzoquinone 

Relevant articles and documents

Effect of Arylthiolated 2,3-Dimethoxy-1,4-benzoquinones on Respiratory Activity and Lipid Peroxidation in Bovine Heart Mitochondria

A series of arylthiolated 2,3-dimethoxy-1,4-benzoquinones was synthesized and tested for the effect on the respiratory system and the lipid peroxidation in bovine heart mitochondria (BHM). These quinones showed intense inhibitory activities on the respiratory system in BHM. Their inhibitory activity in the succinate oxidase system was greater than that in the NADH oxidase system. No difference between the difference spectra, with and without these quinones, of the reduced minus oxidized forms of cytochromes (cyt.) suggested that these quinones inhibit at the site after cyt. a+a3 in the respiratory chain. Moreover, these quinones were as efficient as exogenous ubiquinone-10 (UQ-10) for the inhibition of lipid peroxidation. 5- And 5,6-di-arylthio groups on the quinone ring were found to be favorable for inhibition of the respiratory system and lipid peroxidation. Our results suggest that arylthiolated 2,3-dimethoxy-1,4-benzoquinones act as antioxidants by increasing the amount of endogenous reduced UQ-10 in BHM.