68181-03-3

Basic information

• Product Name: (E)-N-benzylidene-3-phenylpropanehydrazide
• Synonyms: (E)-N-benzylidene-3-phenylpropanehydrazide
• CAS NO: 68181-03-3
• Molecular Formula: C₁₆H₁₆N₂O
• Molecular Weight: 252.31104
• Mol File: 68181-03-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-N-benzylidene-3-phenylpropanehydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-N-benzylidene-3-phenylpropanehydrazide(68181-03-3)
• EPA Substance Registry System: (E)-N-benzylidene-3-phenylpropanehydrazide(68181-03-3)

Safety Data

• Hazardous Substances Data: 68181-03-3(Hazardous Substances Data)

Upstream product

• 3538-68-9 3-phenylpropanehydrazide 
• 100-52-7 benzaldehyde 
• 2021-28-5 ethyl dihydrocinnamate 

Downstream Products

• 1252072-91-5 N-(4-oxo-2-phenylthiazolidin-3-yl)-3-phenylpropanamide 

Relevant articles and documents

Antimicrobial evaluation of imines and thiazolidinones derived from 3-phenylpropane hydrazide

Methyl 3-phenylpropanoate (1), after hydrazination into 3-phenylpropanehydrazide (2), was converted into N-arylidene-3-phenylpropane hydrazides (3a-e), which on cyclization with thioglycolic acid yielded N-(4-oxo-2-arylthiazolidin-3-yl)-3-phenylpropanamides (4a-e). All the proposed structures of newly synthesized compounds were in full agreement with the spectral data. Due to para substitution, compound 3a, 4a and 4b were found to be the most potent when evaluated for antibacterial and antifungal activities.