682153-82-8

Basic information

• Product Name: C₂₈H₃₁NO₄
• CAS NO: 682153-82-8
• Molecular Weight: 445.558
• Mol File: 682153-82-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₈H₃₁NO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₃₁NO₄(682153-82-8)
• EPA Substance Registry System: C₂₈H₃₁NO₄(682153-82-8)

Safety Data

• Hazardous Substances Data: 682153-82-8(Hazardous Substances Data)

Downstream Products

• 6901-16-2 (-)-argemonine 
• 529-79-3 C₂₀H₂₃NO₄ 

Relevant articles and documents

An Enantioselective Access to 1-Alkyl-1,2,3,4-tetrahydroisoquinolines. Application to a New Synthesis of (-)-Argemonine

Potassium ferricyanide oxidation of salt 1 gave isoquinolinone 7 whose treatment with Grignard reagents resulted in a high-yield formation of substituted isoquinolinium salts 5. The selectivity of the reduction of these salts to give derivatives 6 has been studied. Particularly good selectivities (82-84%) were observed when R is a benzylic group. On the basis of these results, a practical and enantioselective synthesis of the natural alkaloid (-)-argemonine is presented.