68279-09-4

Basic information

• Product Name: N-(4-bromophenyl)-α-(4-phenyl)-nitrone
• CAS NO: 68279-09-4
• Molecular Weight: 276.132
• Mol File: 68279-09-4.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: N-(4-bromophenyl)-α-(4-phenyl)-nitrone(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-bromophenyl)-α-(4-phenyl)-nitrone(68279-09-4)
• EPA Substance Registry System: N-(4-bromophenyl)-α-(4-phenyl)-nitrone(68279-09-4)

Safety Data

• Hazardous Substances Data: 68279-09-4(Hazardous Substances Data)

Upstream product

• 3623-23-2 4-bromonitrosobenzene 
• 100-52-7 benzaldehyde 
• 586-78-7 para-nitrophenyl bromide 
• 10468-46-9 N-(4-bromophenyl)hydroxylamine 
• 1137-96-8 N-(benzylidene)aniline N-oxide 

Downstream Products

• 1215859-40-7 C₂₈H₂₄BrNO₅ 
• 1215859-45-2 C₂₈H₂₃BrClNO₅ 

Relevant articles and documents

Rhodium-catalyzed cyclization of diynes with nitrones: A formal [2+2+5] approach to bridged eight-membered heterocycles

N-aryl-substituted nitrones were employed as fiveatom coupling partners in the rhodium-catalyzed cyclization with diynes. In this reaction, the nitrone moiety served as a directing group for the catalytic C-H activation of the N-aryl ring. This formal [2+2+5] approach allows rapid access to bridged eight-membered heterocycles with broad substrate scope. The results of this study may provide new insight into the chemistry of nitrones and find applications in the synthesis of other heterocycles,.

Tandem Chiral Cu(II) Phosphate-Catalyzed Deoxygenation of Nitrones/Enantioselective Povarov Reaction with Enecarbamates

A new catalytic enantioselective tandem deoxygenation/aza-Diels-Alder reaction of nitrones with enecarbamates was serendipitously discovered in the presence of chiral copper(II) diphosphate complexes. This process affords a wide range of 4-aminotetrahydroquinolines in respectable yields under mild conditions with good to excellent ee values.

Synthesis of Benzimidazolones via One-Pot Reaction of Hydroxylamines, Aldehydes, and Trimethylsilyl Cyanide Promoted by Diacetoxyiodobenzene

A novel and efficient PhI(OAc)2-promoted one-pot reaction of aromatic hydroxylamines, aldehydes, and TMSCN in the presence of BF3·Et2O is described. A wide variety of N-substituted benzimidazolones are obtained with satisfactory yields under mild reaction conditions. The method was proven to be efficient for the synthesis of benzimidazolone derivatives from readily available starting materials.