68280-74-0

Basic information

• Product Name: benzyl N⁶-((benzyloxy)carbonyl)-N²-(tert-butoxycarbonyl)-L-lysyl-L-prolinate
• Synonyms: benzyl N⁶-((benzyloxy)carbonyl)-N²-(tert-butoxycarbonyl)-L-lysyl-L-prolinate
• CAS NO: 68280-74-0
• Molecular Weight: 567.682
• Mol File: 68280-74-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: benzyl N⁶-((benzyloxy)carbonyl)-N²-(tert-butoxycarbonyl)-L-lysyl-L-prolinate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl N⁶-((benzyloxy)carbonyl)-N²-(tert-butoxycarbonyl)-L-lysyl-L-prolinate(68280-74-0)
• EPA Substance Registry System: benzyl N⁶-((benzyloxy)carbonyl)-N²-(tert-butoxycarbonyl)-L-lysyl-L-prolinate(68280-74-0)

Safety Data

• Hazardous Substances Data: 68280-74-0(Hazardous Substances Data)

Upstream product

• 2389-45-9 Boc-Lys(Z)-OH 
• 16652-71-4 benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride 
• 84890-96-0 C₂₄H₃₆N₂O₈ 
• 41324-66-7 H-Pro-OBzl 
• 37787-77-2 Boc-L-proline benzyl ester 
• 147-85-3 L-proline 
• 100-51-6 benzyl alcohol 

Downstream Products

• 53157-73-6 Boc-Lys(Z)-Pro-OH 
• 68280-75-1 benzyl N'-((benzyloxy)carbonyl)-L-lysyl-L-prolinate 
• 68280-76-2 benzyl N⁶-((benzyloxy)carbonyl)-L-lysyl-L-prolinate trifluoroacetate 

Relevant articles and documents

Inhibition of urease enzyme activity by urea and thiourea derivatives of dipeptides conjugated 2, 3-dichlorophenyl piperazine

Objective: Studies on enzyme inhibition remain an important area of pharmaceutical research since these studies have led to the discoveries of drugs used in a variety of physiological conditions. In search of novel urease enzyme inhibitors, four dipeptide

Solution-phase automated synthesis of tripeptide derivatives

An improved general method for automated synthesis of tripeptides was developed, in which methanesulfonic acid (MSA) was used in place of trifluoroacetic acid (TFA), thus making it possible to avoid, 1) corrosion of the apparatus by strong acid vapor, 2) formation of emulsions, and 3) use of the restricted solvent, dichloromethane. As an application of the automated synthesis apparatus, 216 fragment tripeptide derivatives were synthesized systematically using the MSA method, in excellent yield and with increased efficiency.

Synthesis and activity of NAcSerAspLysPro analogues on cellular interactions between T-cell and erythrocytes in rosette formation

Analogues of NAcSerAspLysPro (AcSDKP), a natural regulator of hematopoiesis isolated from fetal calf bone marrow, were synthesized. The biological activity of these molecules were evaluated in vitro in the rosette assay, which measures the interaction bet