68282-52-0

Basic information

• Product Name: 2,5-Dimethyl-1H-imidazole-4-carboxaldehyde
• Synonyms: 1H-Imidazole-4-carboxaldehyde, 2,5-dimethyl- (9CI);2,5-Dimethy -1H-Imidazole-4-Carboxaldehyde;2,5-Dimethyl-1H-imidazole-4-carboxaldehyde;5-DiMethyl-1H-iMidazole-4-carboxaldehyde;1H-IMidazole-5-carboxaldehyde, 2,4-diMethyl-;2,5-diMethyl-1H-iMidazole-4-carbaldehyde;2,4-DiMethyl-1H-iMidazole-5-carbaldehyde
• CAS NO: 68282-52-0
• Molecular Formula: C₆H₈N₂O
• Molecular Weight: 124.14
• Product Categories: ALDEHYDE
• Mol File: 68282-52-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 159-161 °C
• Boiling Point: 365.377°C at 760 mmHg
• Flash Point: 178.437°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.583
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 12.04±0.10(Predicted)
• CAS DataBase Reference: 2,5-Dimethyl-1H-imidazole-4-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dimethyl-1H-imidazole-4-carboxaldehyde(68282-52-0)
• EPA Substance Registry System: 2,5-Dimethyl-1H-imidazole-4-carboxaldehyde(68282-52-0)

Safety Data

• Hazardous Substances Data: 68282-52-0(Hazardous Substances Data)

Usage

General Description

2,5-Dimethyl-1H-imidazole-4-carboxaldehyde, also known as DMI, is a chemical compound with a molecular formula C6H8N2O. It is a white to light yellow crystalline powder that is commonly used as an intermediate in the synthesis of pharmaceuticals, especially for antifungal drugs. DMI has a wide range of applications, including as a corrosion inhibitor, a pesticide, and a photoinitiator in UV-curable coatings. It is also used in the manufacturing of rubber and plastic products. DMI is known for its high reactivity and stability, making it a versatile compound in various industries. However, it is important to handle DMI with caution, as it is irritant to the skin, eyes, and respiratory system, and can cause allergic reactions in some individuals.

InChI:InChI=1/C6H8N2O/c1-4-6(3-9)8-5(2)7-4/h3H,1-2H3,(H,7,8)

Upstream product

• 68283-57-8 2,4-dimethyl-5-(hydroxymethyl)imidazole 
• 108512-06-7 N-(3-methyl-4-isoxazolyl)acetamide 
• 68283-57-8 (2,5-dimethyl-1⁽³⁾H-imidazol-4-yl)-methanol 

Downstream Products

• 56536-44-8 1H-5-Acetyl-2,4-dimethylimidazole 
• 856418-36-5 2-(2-(1-benzyl-4-piperidinyl)ethyl)-5,7-dimethyl-1,2-dihydro-3H-imidazo[1,5-c]imidazol-3-one 

Relevant articles and documents

IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF

Imidazole compounds represented by general formula (I): wherein each symbol is as defined in the specification, and salts thereof, and a pharmaceutical composition containing same are provided. These compounds are useful in treating the diseases curable based on a hypoglycemic action, and the diseases curable based on a cGMP-PDE inhibitory action, a smooth muscle relaxing action, a bronchodilating action, a vasodilating action, a smooth muscle cell inhibitory action and an allergy inhibitory action.

Synthesis of 4(5)-Acyl-, 1-Substituted 5-Acyl, and 1-Substituted 4-Acyl-1H-imidazoles from 4-Aminoisoxazoles

4-Aminoisoxazoles can be acylated with a wide variety of activated carboxylic acids.Hydrogenation of the resulting amides gives α-(acylamino)enaminones, which cyclize to 4(5)-acylimidazoles upon treatment with base.This method allows for the synthesis of acylimidazoles with a wide range of substituents at C-2.Utilization of N-substituted 4-aminoisoxazoles in the same sequence of reactions yields 1-substituted 5-acylimidazoles, a substitution pattern not otherwise easily prepared.Treatment of α-(acylamino)enaminones, derived from N-unsubstituted isoxazoles, with primary amines leads to incorporation of the amine at the β-position with concomitant expulsion of ammonia.This sequence efficiently yields 1-substituted and 1,2-disubstituted 4-acylimidazoles but does not give satisfactory yields of 5-substituted 4-acylimidazoles due to steric inhibition of the amine exchange.

Method for the control of undesired plant species using imidazo-as-triazinones and triazine-thiones

This disclosure describes herbicidal methods for the pre- and postemergence control of undesired mono- and dicotyledonous plants using substituted imidazo[1,5-d]-as-triazin-4(3H)-ones and substituted imidazo[1,5-d]-as-triazine-4(3H)-thiones.