68290-83-5Relevant articles and documents
Synthesis of pyrimidines via base-induced condensation of α-chloro oxime derivatives
Tsuritani, Takayuki,Shinokubo, Hiroshi,Oshima, Koichiro
, p. 122 - 123 (2007/10/03)
A facile synthesis of 2,4,6-trisubstituted pyrimidines from the reaction of α-chloro oxime ethers with Grignard reagents has been developed. Alkyl and aryl groups can be easily introduced at the 2-position of the pyrimidine core. In addition, a synthesis of unsymmetrical pyrimidines has been examined.