6837-99-6 Usage
Description
3-AMINO-N-BUTYLBENZAMIDE, a benzamide derivative with the molecular formula C11H15N3O, is a chemical compound that has garnered attention for its potential as an inhibitor of the enzyme poly(ADP-ribose) polymerase (PARP). Its unique structure and properties have positioned it as a promising candidate in the realm of drug discovery and development, particularly in the context of cancer treatment and neuroprotection.
Uses
Used in Pharmaceutical Industry:
3-AMINO-N-BUTYLBENZAMIDE is used as a potential PARP inhibitor for its role in cancer treatment. It targets the enzyme poly(ADP-ribose) polymerase, which is involved in DNA repair mechanisms, making it a candidate for treating cancers that rely on these mechanisms for survival and proliferation.
Used in Cancer Treatment:
3-AMINO-N-BUTYLBENZAMIDE is utilized as an anticancer agent, particularly for cancers that have defects in DNA repair pathways. Its inhibition of PARP can lead to the accumulation of DNA damage in cancer cells, ultimately resulting in cell death. This makes it a valuable tool in the development of targeted therapies for specific cancer types.
Used in Neuroprotection and Anti-Inflammatory Research:
3-AMINO-N-BUTYLBENZAMIDE is employed as a compound of interest in neuroprotective and anti-inflammatory studies. Its potential to protect neurons and reduce inflammation makes it a candidate for the treatment of neurodegenerative diseases and conditions involving inflammation in the central nervous system.
Check Digit Verification of cas no
The CAS Registry Mumber 6837-99-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,8,3 and 7 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6837-99:
(6*6)+(5*8)+(4*3)+(3*7)+(2*9)+(1*9)=136
136 % 10 = 6
So 6837-99-6 is a valid CAS Registry Number.
6837-99-6Relevant articles and documents
3-(2′-Bromopropionylamino)-benzamides as novel S-phase arrest agents
Hu, Laixing,Li, Zhuo-rong,Li, Jian-Nong,Qu, Jinrong,Jiang, Jian-Dong,Boykin, David W.
, p. 6847 - 6852 (2008/09/16)
We report the synthesis, antiproliferative activity, and SAR of novel 3-(2′-bromopropionylamino)-benzamides. Many of the benzamide compounds showed potent cytotoxicities against Molt-3 leukemia cells. Several compounds exihibited cytotoxicities (under 6.5
