683739-37-9

Basic information

• Product Name: 2-BroMo-N-phenylbenzenesulfonaMide, 97%
• Synonyms: 2-BroMo-N-phenylbenzenesulfonaMide, 97%
• CAS NO: 683739-37-9
• Molecular Weight: 312.187
• Mol File: 683739-37-9.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 2-BroMo-N-phenylbenzenesulfonaMide, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BroMo-N-phenylbenzenesulfonaMide, 97%(683739-37-9)
• EPA Substance Registry System: 2-BroMo-N-phenylbenzenesulfonaMide, 97%(683739-37-9)

Safety Data

• Hazardous Substances Data: 683739-37-9(Hazardous Substances Data)

Upstream product

• 576-92-1 bromobenzene-2-sulfonic acid 
• 62-53-3 aniline 
• 98-95-3 nitrobenzene 
• 244205-40-1 (2-bromophenyl)boronic acid 
• 2905-25-1 o-bromobenzenesulfonyl chloride 

Downstream Products

• 1090618-37-3 N-phenyl-2-bromo-N-ethylbenzenesulfonamide 
• 18963-39-8 N-phenyl-2-(phenylethynyl)benzenesulfonamide 

Relevant articles and documents

Copper-Catalyzed Aminoarylation of Alkenes via Aminyl Radical Addition and Aryl Migration

We describe a new strategy for aminoarylation of alkenes by copper-catalyzed smiles rearrangement using O-benzoylhydroxylamines as the amine reagent. This method affords various β-amino amide derivatives possessing a quaternary carbon center with wide functional group tolerance and high regioselectivity. The mechanistic studies indicate that the transformation can involve aminyl radical intermediates under acid-free condition.

O-cyclopropyl benzenesulfonyl aniline and preparation method thereof

The invention discloses an o-cyclopropyl benzenesulfonyl aniline and a preparation method thereof. The preparation method comprises the steps: dissolving 2-bromobenzenesulfonic acid and aniline in pyridine, then adding a condensing agent EDC-HCl, and carrying out a reaction for 2 to 4 h at a temperature of 60 to 80 DEG C so as to obtain 2-bromo-N-phenylbenzenesulfonamide; dissolving 2-bromo-N-phenylbenzenesulfonamide into a dioxane solution; adding cyclopropylboronic acid, sodium carbonate, an aqueous solution, Pd(dppf)Cl2 and a mixed system, carrying out a reaction at a temperature of 110 DEGC for 8-10 h in a nitrogen atmosphere, and carrying out after-treatment to obtain o-cyclopropyl benzenesulfonyl aniline. The synthesis route disclosed by the invention is short, only two-step reaction is carried out, and the reaction is easy to operate; the used preparation method is strong in operability and high in yield, and is an excellent method suitable for large-scale preparation. Becausethe compounds are valuable drug intermediates, the o-cyclopropyl benzenesulfonyl aniline has important research and practical values.

Cyclic Hypervalent Iodine Reagents for Azidation: Safer Reagents and Photoredox-Catalyzed Ring Expansion

Azides are building blocks of increasing importance in synthetic chemistry, chemical biology, and materials science. Azidobenziodoxolone (ABX, Zhdankin reagent) is a valuable azide source, but its safety profile has not been thoroughly established. Herein, we report a safety study of ABX, which shows its hazardous nature. We introduce two derivatives, tBu-ABX and ABZ (azidobenziodazolone), with a better safety profile, and use them in established photoredox- and metal-mediated azidations, and in a new ring-expansion of silylated cyclobutanols to give azidated cyclopentanones.