68407-07-8

Basic information

• Product Name: 3-[2-(2-MALEIMIDOETHOXY)ETHYLCARBAMOYL]-PROXYL
• Synonyms: 3-[2-(2-MALEIMIDOETHOXY)ETHYLCARBAMOYL]-2,2,5,5-TETRAMETHYL-1-PYRROLIDINYLOXY;3-[2-(2-MALEIMIDOETHOXY)ETHYLCARBAMOYL]-PROXYL;3-(2-(2-MALEIMIDOETHOXY)ETHYLCARBAMOYL)- PROXYL, FREE RADICAL;3-([(2-[2-(2,5-dihydro-2,5-dioxo-1h-pyrrol-1-yl)ethoxy]ethyl)amino]carbonyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy;3-[2-(2-Maleimidoethoxy)ethylcarbamoyl]-2,2,5,5-tetramethyl-1-pyrrolidinyloxy, free radical, 3-([(2-[2-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethyl)amino]carbonyl)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy
• CAS NO: 68407-07-8
• Molecular Formula: C17H26N3O5 *
• Molecular Weight: 352.41
• Mol File: 68407-07-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 95-98 °C(lit.)
• Boiling Point: 567.3 °C at 760 mmHg
• Flash Point: 296.9 °C
• Appearance: /
• Density: 1.211g/cm³
• Vapor Pressure: 2.36E-14mmHg at 25°C
• Refractive Index: 1.533
• Storage Temp.: 0-6°C
• CAS DataBase Reference: 3-[2-(2-MALEIMIDOETHOXY)ETHYLCARBAMOYL]-PROXYL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[2-(2-MALEIMIDOETHOXY)ETHYLCARBAMOYL]-PROXYL(68407-07-8)
• EPA Substance Registry System: 3-[2-(2-MALEIMIDOETHOXY)ETHYLCARBAMOYL]-PROXYL(68407-07-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 68407-07-8(Hazardous Substances Data)

Usage

Description

3-[2-(2-MALEIMIDOETHOXY)ETHYLCARBAMOYL]-PROXYL is a stable nitroxide radical and a chemical compound commonly used as a spin label in biochemical and medical research. It is particularly valuable for studying the structure and dynamics of proteins, nucleic acids, and membranes through electron paramagnetic resonance (EPR) spectroscopy. The presence of a maleimidoethoxy group in its structure enables specific labeling of cysteine residues in proteins, making it an ideal tool for investigating protein-protein interactions and conformational changes. Its stability and relatively long half-life in biological systems also make it suitable for long-term studies of physiological processes.

Uses

Used in Biochemical Research:
3-[2-(2-MALEIMIDOETHOXY)ETHYLCARBAMOYL]-PROXYL is used as a spin label for studying the structure and dynamics of various biological molecules, such as proteins, nucleic acids, and membranes. Its application in electron paramagnetic resonance (EPR) spectroscopy allows researchers to gain insights into molecular interactions and conformational changes.
Used in Medical Research:
In the medical field, 3-[2-(2-MALEIMIDOETHOXY)ETHYLCARBAMOYL]-PROXYL is used as a specific labeling agent for cysteine residues in proteins. This enables researchers to investigate protein-protein interactions and monitor conformational changes, which can be crucial for understanding disease mechanisms and developing therapeutic strategies.
Used in Long-term Physiological Studies:
Due to its stability and relatively long half-life in biological systems, 3-[2-(2-MALEIMIDOETHOXY)ETHYLCARBAMOYL]-PROXYL is used as a valuable tool for long-term studies of physiological processes. This allows researchers to monitor changes over time and gain a deeper understanding of the complex dynamics involved in various biological systems.

InChI:InChI=1/C17H27N3O5/c1-16(2)11-12(17(3,4)20(16)24)15(23)18-7-9-25-10-8-19-13(21)5-6-14(19)22/h5-6,12,24H,7-11H2,1-4H3,(H,18,23)/t12-/m1/s1