68423-35-8

Basic information

• Product Name: ethyl 3-formylphenyl carbonate
• CAS NO: 68423-35-8
• Molecular Formula: C₁₀H₁₀O₄
• Molecular Weight: 194.184
• Mol File: 68423-35-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 308.5°C at 760 mmHg
• Flash Point: 135.6°C
• Density: 1.201g/cm³
• Vapor Pressure: 0.00068mmHg at 25°C
• Refractive Index: 1.54
• CAS DataBase Reference: ethyl 3-formylphenyl carbonate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-formylphenyl carbonate(68423-35-8)
• EPA Substance Registry System: ethyl 3-formylphenyl carbonate(68423-35-8)

Safety Data

• Hazardous Substances Data: 68423-35-8(Hazardous Substances Data)

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 100-83-4 meta-hydroxybenzaldehyde 

Downstream Products

• 26207-63-6 5,7,3'-Trihydroxyflavanone 
• 42454-06-8 2-nitro-5-hydroxybenzaldehyde 
• 58662-54-7 5-benzyloxy-2-nitrobenzaldehyde 
• 68423-36-9 (5-(benzyloxy)-2-nitrophenyl)methanol 
• 68423-37-0 2-Nitro-5-(benzyloxy)-benzylchlorid 
• 80172-02-7 3-ethoxycarbonyloxybenzoic acid 

Relevant articles and documents

SUPRAMOLECULAR PROTEIN ASSEMBLIES WITH ADVANCED FUNCTIONS AND SYNTHESIS THEREOF

The present invention discloses stimuli-sensitive protein conjugate which can make supramolecular protein assemblies and methods for using the same. The present invention provides simple and rational process for construction of said stimuli-sensitive spherical protein assemblies through supramolecular chemical strategy.

Crystal structure of the Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex: Insights into the molecular basis of kynureninase substrate specificity

Homo sapiens kynureninase is a pyridoxal-5'-phosphate dependent enzyme that catalyzes the hydrolytic cleavage of 3-hydroxykynurenine to yield 3-hydroxyanthranilate and L-alanine as part of the tryptophan catabolic pathway leading to the de novo biosynthesis of NAD+. This pathway results in quinolinate, an excitotoxin that is an NMDA receptor agonist. High levels of quinolinate have been correlated with the etiology of neurodegenerative disorders such as AIDS-related dementia and Alzheimer's disease. We have synthesized a novel kynureninase inhibitor, 3-hydroxyhippurate, cocrystallized it with human kynureninase, and solved the atomic structure. On the basis of an analysis of the complex, we designed a series of His- 102, Ser-332, and Asn-333 mutants. The H102W/N333T and H102W/S332G/N333T mutants showed complete reversal of substrate specificity between 3-hydroxykynurenine and L-kynurenine, thus defining the primary residues contributing to substrate specificity in kynureninases.