6850-60-8

Basic information

• Product Name: 4-ETHOXY-BENZYLAMINE
• Synonyms: RARECHEM AL BW 0170;4-ETHYLOXYBENZYLAMINE;4-ETHOXY-BENZYLAMINE;AKOS BC-2641;Albb-005371;(4-Ethoxyphenyl)MethanaMine
• CAS NO: 6850-60-8
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.21
• Mol File: 6850-60-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: 191 °C
• Boiling Point: 248.8°C at 760 mmHg
• Flash Point: 106.2°C
• Appearance: /
• Density: 1.008g/cm³
• Vapor Pressure: 0.0238mmHg at 25°C
• Refractive Index: 1.525
• Storage Temp.: 2-8°C(protect from light)
• PKA: 9.32±0.10(Predicted)
• CAS DataBase Reference: 4-ETHOXY-BENZYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ETHOXY-BENZYLAMINE(6850-60-8)
• EPA Substance Registry System: 4-ETHOXY-BENZYLAMINE(6850-60-8)

Safety Data

• Hazard Codes: Xi
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 6850-60-8(Hazardous Substances Data)

Usage

General Description

4-Ethoxy-benzylamine is an organic compound with the chemical formula C9H13NO. It is a secondary amine with a benzyl group that is substituted with an ethoxy group at the ortho position. 4-ETHOXY-BENZYLAMINE is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its versatile reactivity and ability to participate in various organic reactions. It is also used as an intermediate in the manufacturing of dyes, pigments, and other chemical substances. 4-Ethoxy-benzylamine is a clear, colorless to pale yellow liquid with a faint odor, and it is considered to be a hazardous substance that should be handled with care.

InChI:InChI=1/C9H13NO/c1-2-11-9-5-3-8(7-10)4-6-9/h3-6H,2,7,10H2,1H3

Upstream product

• 3424-93-9 4-methoxyphenylacetamide 
• 25117-74-2 4-ethoxybenzonitrile 
• 6653-80-1 4-ethoxybenzylchloride 
• 89074-22-6 p-ethoxybenzylidenemethylamine 

Downstream Products

• 18636-22-1 1-ethoxy-4-(isothiocyanatomethyl)benzene 
• 103565-47-5 (4-ethoxy-benzyl)-carbamic acid methyl ester 
• 85501-73-1 N-[4-Chloro-6-(4-ethoxy-benzylamino)-2-methyl-pyrimidin-5-yl]-acetamide 
• 101587-92-2 N-(4-ethoxy-benzyl)-N'-(4-methoxy-phenyl)-thiourea 
• 15437-14-6 N-(4-ethoxyphenyl)benzamide 

Relevant articles and documents

Benzylguanidines and other galegine analogues inducing weight loss in mice

Dimethylallylguanidine, also known as galegine, isolated from Galega officinalis, has been shown to have weight reducing properties in vivo. Substitution of the guanidine group with an N-cyano group and replacement of guanidine with amidine, pyrimidine, pyridine, or the imidazole moieties removed the weight reducing properties when evaluated in BALB/c mice. However, retention of the guanidine and replacement of the dimethylallyl group by a series of functionalized benzyl substituents was shown to exhibit, and in some cases significantly improve, the weight reducing properties of these molecules in BALB/c, ob/ob, and diet induced obesity (DIO) mice models. The lead compound identified, across all models, was 1-(4-chlorobenzyl)guanidine hemisulfate, which gave an average daily weight difference (% from time-matched controls; ± SEM) of -19.7 ± 1.0, -11.0 ± 0.7, and -7.3 ± 0.8 in BALB/c, ob/ob, and DIO models, respectively.