68528-29-0

Basic information

• Product Name: 2-Furancarboxaldehyde, 5-[4-(methylsulfonyl)phenyl]-
• CAS NO: 68528-29-0
• Molecular Formula: C12H10O4S
• Molecular Weight: 250.275
• Mol File: 68528-29-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Furancarboxaldehyde, 5-[4-(methylsulfonyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Furancarboxaldehyde, 5-[4-(methylsulfonyl)phenyl]-(68528-29-0)
• EPA Substance Registry System: 2-Furancarboxaldehyde, 5-[4-(methylsulfonyl)phenyl]-(68528-29-0)

Safety Data

• Hazardous Substances Data: 68528-29-0(Hazardous Substances Data)

Upstream product

• 1899-24-7 5-bromo-2-furancarboxaldehyde 
• 149104-88-1 4-methanesulphonylphenylboronic acid 

Downstream Products

• 873659-49-5 (E)-3-[5-(4-methylsulfonylphenyl)-2-furyl]acrylic acid chloride 
• 765937-85-7 3-[5-(4-methylsulfonylphenyl)-2-furyl]acrylic acid 

Relevant articles and documents

CYCLIC CARBOXYLIC ACID RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF TUBERCULOSIS

Disclosed are methods for the prevention or treatment of tuberculosis in a subject infected with Mycobacterium tuberculosis by administering rhodanine derivatives of formula (I), as well as some novel such compounds. Other embodiments are also disclosed.

Structure-activity relationships of novel anti-malarial agents part 8. Effect of different central aryls in biarylacryloylaminobenzophenones on antimalarial activity

Replacement of the 2,5-disubstituted furyl residue present in the known antimalarial agents 8 by other aryl residues resulted in a more or less reduced antimalarial activity in most cases. The only exemption was the 2,4-thienylene compound 11a displaying activity with an IC50 value of 120 nM. In conclusion, the 2,5-furylene compound 8e remains to represent the most active antimalarial agent in this series of farnesyltransferase inhibitors.