68578-51-8

Basic information

• Product Name: chloro-1 ethoxymethyl-2-benzene
• Synonyms: chloro-1 ethoxymethyl-2-benzene
• CAS NO: 68578-51-8
• Molecular Weight: 170.639
• Mol File: 68578-51-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: chloro-1 ethoxymethyl-2-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: chloro-1 ethoxymethyl-2-benzene(68578-51-8)
• EPA Substance Registry System: chloro-1 ethoxymethyl-2-benzene(68578-51-8)

Safety Data

• Hazardous Substances Data: 68578-51-8(Hazardous Substances Data)

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 79411-60-2 l'α-chloro α-ethoxymethyltributyletain 
• 998-30-1 Triethoxysilane 
• 611-17-6 1-bromomethyl-2-chlorobenzene 
• 7664-93-9 sulfuric acid 
• 7335-25-3 ethyl 2-chlorobenzoate 

Relevant articles and documents

Highly efficient indium-catalyzed chemoselective allylation-etherification and reductive etherification of aromatic aldehydes with functional silanes

Indium(III) chloride is an effective Lewis acid catalyst for one-pot allylation-etherification and reductive etherification of aromatic aldehydes with functional silanes, allyltriethoxysilane, and triethoxysilane, at room temperature to afford corresponding ethers in excellent yields. Additionally, the InCl3-catalyzed reactions in the presence of TMSCl offer significant advantages in its ease of working-up for the preparation of unsymmetrical ethers under mild conditions.

Preparation of biaryl compounds

A method for the preparation of biaryl compounds is disclosed which comprises contacting an aryl halide with a tertiary-alkyl organometallic reagent (or the precursor components thereof) in the presence of a catalyst comprising a nickel compound and a coordinating ligand under conditions suitable for the formation of biaryl compound. In an alternative embodiment of the present invention, nickel(0) compounds are prepared from nickel(II) compounds by contacting a nickel(II) compound with a combination of an organophosphine and a bidentate nitrogen-containing coordinating ligand, and a tertiary-alkyl organometallic reagent (or the precursor components thereof) in an aprotic, non-polar, ether-containing solvent system for a time and under conditions suitable for the formation of nickel(0) compound.

QUELQUES ASPECTS DE LA REACTIVITE DE L'α-CHLORO α-ETHOXYMETHYLTRIBUTYLETAIN: ETHERIFICATION REDUCTRICE DES ALDEHYDES AROMATIQUES ET MISE EN EVIDENCE DE FORMYLTRIBUTYLETAIN LORS DE LA REACTION D'HYDROLYSE

α-Chloro-α-ethoxymethyltributyltin reacts with aromatic aldehydes and leads to benzyl ethyl ethers with formation of tributyltin chloride and carbon monoxide.Analogously the formation of ethoxymethyltributyltin and tributyltyn chloride on hydrolysis of this new organometallic reagent is explained by a process involving formyltributyltin as an unstable intermediate.This explanation is supported by the observation of an electronic spectrum between 350 and 450 nm during the hydrolysis.