68671-47-6

Basic information

• Product Name: p-nitrophenyl-D-lactic acid
• Synonyms: p-nitrophenyl-D-lactic acid
• CAS NO: 68671-47-6
• Molecular Weight: 211.174
• Mol File: 68671-47-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: p-nitrophenyl-D-lactic acid(CAS DataBase Reference)
• NIST Chemistry Reference: p-nitrophenyl-D-lactic acid(68671-47-6)
• EPA Substance Registry System: p-nitrophenyl-D-lactic acid(68671-47-6)

Safety Data

• Hazardous Substances Data: 68671-47-6(Hazardous Substances Data)

Usage

General Description

p-nitrophenyl-D-lactic acid is a chemical compound that belongs to the class of nitrophenyl derivatives. It is a derivative of D-lactic acid, which is a natural component of certain foods and is also produced in the human body during metabolism. The addition of the p-nitrophenyl group to D-lactic acid creates a compound that is often used in biochemical and pharmacological research. p-nitrophenyl-D-lactic acid is known for its ability to act as a substrate for various enzymatic reactions, and its nitrophenyl group can be used as a chromogenic or fluorogenic label for detecting and measuring enzyme activity. p-nitrophenyl-D-lactic acid has potential applications in drug development, clinical diagnostics, and the study of metabolic pathways.

Upstream product

• 673-06-3 D-(R)-phenylalanine 
• 56613-61-7 (R)-4-nitro-phenylalanine 

Downstream Products

• 155030-66-3 (3S,6R,9S,12R,15S,18R,21S,24R)-3,9,15,21-tetraisobutyl-4,6,10,16,18,22-hexamethyl-12,24-bis(4-aminobenzyl)-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclotetracosan-2,5,8,11,14,17,20,23-octanone 

Relevant articles and documents

ENDOPARASITIC DEPSIPEPTIDES

The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof (1) wherein each of R1, R2, R3, R4, L1, and L2, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.

Synthesis, biological evaluation, and molecular modeling investigation of chiral 2-(4-chloro-phenoxy)-3-phenyl-propanoic acid derivatives with PPARα and PPARγ agonist activity

PPARs are ligand-activated transcription factors that govern lipid and glucose homeostasis and play a central role in cardiovascular disease, obesity, and diabetes. Herein, we present screening results for a series of chiral 2-(4-chloro-phenoxy)-3-phenyl-propanoic acid derivatives, some of which are potent PPARγ agonists as well as PPARα agonists. To investigate the binding modes of the most interesting derivatives into the PPARα and PPARγ binding clefts and evaluate their agonist activity, docking experiments, molecular dynamics simulations, and MM-PBSA analysis were performed.