689300-85-4

Basic information

• Product Name: Benzenamine, 2-chloro-N-methyl-4-(trifluoromethyl)-
• CAS NO: 689300-85-4
• Molecular Formula: C8H7ClF3N
• Molecular Weight: 209.598
• Mol File: 689300-85-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenamine, 2-chloro-N-methyl-4-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2-chloro-N-methyl-4-(trifluoromethyl)-(689300-85-4)
• EPA Substance Registry System: Benzenamine, 2-chloro-N-methyl-4-(trifluoromethyl)-(689300-85-4)

Safety Data

• Hazardous Substances Data: 689300-85-4(Hazardous Substances Data)

Upstream product

• 22864-65-9 N-methyl-4-(trifluoromethyl)aniline 
• 328-84-7 1,2-dichloro-4-(trifluoromethyl)benzene 
• 74-89-5 methylamine 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 69695-61-0 2-chloro-4-(trifluoromethoxy)aniline 

Downstream Products

• 24279-39-8 2,6-dichloro-4-(trifluoromethyl)aniline 
• 156639-47-3 2,6-dichloro-4-trifluoromethyl-N-methylaniline 
• 689300-86-5 (2-chloro-4-trifluoromethoxy-phenyl-amino)-acetic acid ethyl ester 

Relevant articles and documents

Halogenated method of aromatic compound

The invention belongs to the field of organic synthesis, and particularly relates to synthesis of aromatic halogens, in particular to arylamine. The invention discloses a synthesis method of a corresponding ortho-halogenated product from aromatic compounds such as carbazole and phenol. The method comprises the following steps: adding a metal sulfonate salt catalyst, aromatic amine, carbazole, phenol and other hydrogen - heteroatom-containing aromatic compound reaction substrates, a halogenation reagent and a reaction solvent at a specific reaction temperature. After the drying agent is dried, the yield of the reaction product and the nuclear magnetic characterization determining structure are determined by column chromatography. The reaction product yield is determined by gas chromatography. By adopting the method, under the cheap metal salt catalyst, a plurality of ortho-substituted brominated and chloro products can be obtained with moderate to excellent yield.

NOVEL AMIDE COMPOUNDS WITH MCH ANTAGONISTIC EFFECT AND MEDICAMENTS COMPRISING SAID COMPOUNDS

The invention relates to amide compounds of general formula (I), in which the groups and residues A, B, b, W, X, Y, Z, R1, R2 and R3 have the meanings given in claim 1. The invention further relates to medicaments comprising at least one of said amides. Said medicaments are suitable for the treatment of metabolic disorders and/or eating disorders, in particular, obesity, bulimia, anorexia, hyperphagia, and diabetes as a result of the MCH receptor antagonism.