6898-87-9

Basic information

• Product Name: 1,2,5-Oxadiazole, 3-methyl-4-phenyl-, 5-oxide
• CAS NO: 6898-87-9
• Molecular Formula: C9H8N2O2
• Molecular Weight: 176.175
• Mol File: 6898-87-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,2,5-Oxadiazole, 3-methyl-4-phenyl-, 5-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,5-Oxadiazole, 3-methyl-4-phenyl-, 5-oxide(6898-87-9)
• EPA Substance Registry System: 1,2,5-Oxadiazole, 3-methyl-4-phenyl-, 5-oxide(6898-87-9)

Safety Data

• Hazardous Substances Data: 6898-87-9(Hazardous Substances Data)

Usage

Type of compound

Organic compound

Structure

Contains a five-membered 1,2,5-oxadiazole ring

Substituents

a. Methyl group (-CH3) attached to the 3rd position
b. Phenyl group (C6H5) attached to the 4th position

Oxidation state

5-oxide functionality introduces a highly reactive oxygen atom

Parent compound

1,2,5-Oxadiazole

Biological activities

Known for diverse biological activities

Pharmaceutical applications

Potential pharmaceutical applications

Agricultural applications

Research on its potential as an agricultural agent

Advanced materials

Role in the development of advanced materials

Organic electronics

Involvement in the development of organic electronics

Upstream product

• 56-23-5 tetrachloromethane 
• 6898-86-8 3-methyl-4-phenylfuroxan 
• 108-24-7 acetic anhydride 
• 17019-18-0 anti-methylphenylglyoxime 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 93-55-0 1-phenyl-propan-1-one 
• 4937-86-4 1-phenyl-propanedione-(1.2)-1-seqcis-oxime-2-seqtrans-oxime 
• 4937-86-4 1-phenyl-1,2-propanedione dioxime 
• 873-66-5 1-propenylbenzene 

Downstream Products

• 6898-86-8 3-methyl-4-phenylfuroxan 
• 98384-64-6 (3aS,3cS,6aR,8aR)-3b-Methyl-2,5-diphenyl-tetrahydro-7,8-dioxa-2,5,7a-triaza-dicyclopenta[a,f]pentalene-1,3,4,6-tetraone 
• 88059-58-9 4-methyl-3-(2'-nitrophenyl)furoxan 
• 88059-60-3 4-methyl-3-(4'-nitrophenyl)furoxan 
• 88059-59-0 4-methyl-3-(3'-nitrophenyl)furoxan 

Relevant articles and documents

Oxidation of: O -dioxime by (diacetoxyiodo)benzene: Green and mild access to furoxans

Furoxan has been widely used in the field of high energy density materials because of its excellent properties such as high density, high standard enthalpy of formation and high nitrogen content. However, its existing synthesis methods are still restricted by the problems of difficult substrate preparation and manual handling of hazardous reagents. Herein, we disclosed a mild oxidation strategy to efficiently obtain furoxan derivatives starting from readily available o-dioxime substrates. This reaction features high functional group tolerance and easy scale-up, and has excellent regioselectivity for specific nonsymmetric o-dioximes. This method greatly reduces the safety risk and simplifies the operation process, and means that diversified furoxan derivatives can be easily accessed, thus paving the way for the wide application of furoxan derivatives. This journal is

Synthesis of furoxans from styrenes under basic or neutral conditions

Furoxans (1,2,5-oxadiazole 2-oxides) can be synthesized from the corresponding styrenes using NOBF4 under basic or even almost neutral reaction conditions. Acid-sensitive functional groups are tolerated under the developed basic conditions. For

Nitrophenyl derivatives of the furazan and furoxan ring systems

The preparation of some nitrophenyl derivatives of the furazan and furoxan ring systems is reported. The results of an antimicrobial screening on these compounds are also briefly discussed.