69047-41-2Relevant articles and documents
Synthesis and Evaluation of Non-peptidic Cysteine Protease Inhibitors of P. falciparum Derived from Etacrynic Acid
Dude, Marie-Adrienne,Kaeppler, Ulrich,Herb, Monika,Schiller, Markus,Schulz, Franziska,Vedder, Birgit,Heppner, Saskia,Pradel, Gabriele,Gut, Jiri,Rosenthal, Philip J.,Schirmeister, Tanja,Leippe, Matthias,Gelhaus, Christoph
scheme or table, p. 19 - 35 (2009/09/08)
A series of etacrynic acid derivatives was synthesized and screened for their in vitro activity against Plasmodium falciparum, as well as their activity against recombinantly expressed falcipain-2 and -3. The two most active compounds of the series displayed IC50 values of 9.0 and 18.8 μM against Plasmodia.
A New Reagent for Activating Carboxyl Groups; Preparation and Reactions of N,N-Bisphosphorodiamidic Chloride
Diago-Meseguer, J.,Palomo-Coll, A.L.,Fernandez-Lizarbe, J.R.,Zugaza-Bilbao, A.
, p. 547 - 551 (2007/10/02)
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