69048-79-9Relevant articles and documents
A modified Cu(0)-Cu(I)-mediated Caryl-CarylUllmann coupling for the synthesis of biaryls
Yasamut, Kittisak,Jongcharoenkamol, Jira,Ruchirawat, Somsak,Ploypradith, Poonsakdi
, p. 5994 - 6000 (2016/09/14)
A novel Cu(0)-Cu(I)-mediated Caryl-CarylUllmann coupling has been successfully developed. The use of Cu(I) salts allowed the reactions to proceed under relatively mild conditions (65?°C in DMSO for 15–72?h). The developed method was compatible with a relatively wide range of functional groups simultaneously present on the aromatic ring of different electronic nature. The aryl halides with an electron-withdrawing group ortho to the halide or an electron-donating group meta or para to the halide furnished the corresponding products in good to excellent yields (up to 98%).
Synthesis of The Diaza Analogue of Ellagic Acid
Kanojia, Ramesh M.,Ohemeng, Kwasi A.,Schwender, Charles F.,Barrett, John F.
, p. 8553 - 8556 (2007/10/02)
The novel diaza analogue 2 of DNA-gyrase inhibitor ellagic acid 1 was synthesized via the Ullmann coupling of methyl 2-bromo-3-nitroveratrate 6 which, in turn, was prepared by a 7-step synthesis from 2-bromopiperonal 10 requiring a contrived, regiospecifi
