69049-03-2

Basic information

• Product Name: 1-(2-chloroethyl)-4-ethyl-1,4-dihydro-5H-tetrazol-5-one
• Synonyms: 1-(2-chloroethyl)-4-ethyl-1,4-dihydro-5H-tetrazol-5-one;1-(2-Chloroethyl)-4-ethyl...;5H-Tetrazol-5-one, 1-(2-chloroethyl)-4-ethyl-1,4-dihydro-;1-(2-Chloroethyl)-4-ethyl-1H-tetrazol-5(4H)-one;1-(2-chloroethyl)-4-ethyl-4,5-dihydro-1H-1,2,3,4-tetrazol-5-one
• CAS NO: 69049-03-2
• Molecular Formula: C₅H₉ClN₄O
• Molecular Weight: 176.60416
• EINECS: 273-845-8
• Mol File: 69049-03-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 206.6°C at 760 mmHg
• Flash Point: 78.8°C
• Appearance: /
• Density: 1.45g/cm³
• Vapor Pressure: 0.235mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: 1-(2-chloroethyl)-4-ethyl-1,4-dihydro-5H-tetrazol-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-chloroethyl)-4-ethyl-1,4-dihydro-5H-tetrazol-5-one(69049-03-2)
• EPA Substance Registry System: 1-(2-chloroethyl)-4-ethyl-1,4-dihydro-5H-tetrazol-5-one(69049-03-2)

Safety Data

• Hazardous Substances Data: 69049-03-2(Hazardous Substances Data)

Usage

General Description

1-(2-chloroethyl)-4-ethyl-1,4-dihydro-5H-tetrazol-5-one is a chemical compound that contains a tetrazole ring and a chloroethyl group. It is used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. The chloroethyl group has the potential to react with various nucleophiles in a wide range of reactions, making this compound versatile in organic synthesis. Additionally, the tetrazole ring contributes to the compound's biological activity and potential pharmaceutical applications. Overall, this chemical has valuable properties that make it useful in the production of various compounds with diverse applications.

InChI:InChI=1/C5H9ClN4O/c1-2-9-5(11)10(4-3-6)8-7-9/h2-4H2,1H3

Upstream product

• 107-04-0 1-Bromo-2-chloroethane 
• 69048-98-2 1-ethyl-1,4-dihydro-5H-tetrazol-5-one 
• 108-10-1 4-methyl-2-pentanone 
• 107-06-2 1,2-dichloro-ethane 

Downstream Products

• 101344-78-9 trans-1-<2-(4-ethyl-4,5-dihydro-1H-tetrazolyl)ethyl>-3-methyl-4-piperidine 
• 101344-78-9 cis-1-<2-(4-ethyl-4,5-dihydro-1H-tetrazolyl)ethyl>-3-methyl-4-piperidine 
• 98244-83-8 1-ethyl-1,4-dihydro-4-<2-<4-<<1-(phenylmethyl)-1H-benzimidazol-2-yl>amino>-1-piperidinyl>ethyl>-5H-tetrazol-5-one 
• 104072-07-3 N-<1-<2-(4-ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)ethyl>-4-piperidinyl>-N-phenylpropanamide 
• 69049-15-6 alfentanil 
• 69049-16-7 methyl 1-[2-(4-ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)ethyl]-4-[(1-oxopropyl)phenylamino]-4-piperidinecarboxylate ethanedioate 
• 70879-28-6 N-{1-[2-(4-ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)ethyl]-4-(methoxymethyl)-4-piperidinyl}-N-phenylpropanamide monohydrochloride monohydrate 

Relevant articles and documents

Preparation method of alfentanil and sufentan and compounds used for preparation of sufentanil and alfentan

The invention discloses a preparation method of alfentanil and sufentan and compounds used for preparation of sufentanil and alfentan. Specifically, the method for preparation of a compound shown as formula V includes: carrying out BOC reaction on a compound shown as formula IV to obtain the compound shown as formula V in the specification. The method can conveniently, efficiently and safely prepare an intermediate product for synthesis of alfentanil and sufentan, i.e. the compound shown as formula V. And then, the compound shown as formula V can be effectively used for preparation of alfentanil and sufentan.

N-phenyl-N-(4-piperidinyl)amides

Novel compounds of the series of N-phenyl-N-(4-piperidinyl)amides having a (4,5-dihydro-4-R-5-oxo-1H-tetrazol-1-yl)alkyl or (4,5-dihydro-4-R-5-thioxo-1H-tetrazol-1-yl)alkyl substituent group in the 1-position of the piperidine nucleus, said compounds being useful as analgesic agents.