69053-90-3

Basic information

• Product Name: 2-<3-<3-(Trifluoromethyl)phenyl>-2-isoxazol-5-yl>benzoic acid
• Synonyms: 2-<3-<3-(Trifluoromethyl)phenyl>-2-isoxazol-5-yl>benzoic acid
• CAS NO: 69053-90-3
• Molecular Weight: 333.267
• Mol File: 69053-90-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-<3-<3-(Trifluoromethyl)phenyl>-2-isoxazol-5-yl>benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-<3-<3-(Trifluoromethyl)phenyl>-2-isoxazol-5-yl>benzoic acid(69053-90-3)
• EPA Substance Registry System: 2-<3-<3-(Trifluoromethyl)phenyl>-2-isoxazol-5-yl>benzoic acid(69053-90-3)

Safety Data

• Hazardous Substances Data: 69053-90-3(Hazardous Substances Data)

Upstream product

• 69053-89-0 methyl 2-[3-[3-(Trifluoromethyl)-Phenyl]-5-Isoxazolyl]Benzoate 
• 74423-18-0 3'-<3-(trifluoromethyl)phenyl>spiro-3-one 
• 64692-99-5 Sodium salt of 2-carboxybenzaldehyde 
• 28269-50-3 2-vinylbenzoic acid chloride 
• 27326-44-9 methyl o-vinylbenzoate 
• 27326-43-8 2-vinylbenzoic acid 
• 69053-92-5 Methyl 2-<3-<3-(trifluoromethyl)phenyl>-2-isoxazolin-5-yl>benzoate 
• 577-56-0 2-acetyl-benzoic acid 
• 3453-63-2 3-methylidenephthalide 

Relevant articles and documents

3'-Arylspiro-3-ones and Their Conversion to 2-(3-Arylisoxazol-5-yl)benzoates

A new, convenient route to the biologically active 2-(3-arylisoxazol-5-yl)benzoates 4 is reported.This route consists of 1,3-dipolar cycloaddition of aromatic nitrile oxides to 3-methylenephthalide to form the novel 3'-arylspiro-3-ones 3 and subsequent high-yield conversions of 3 to 4.

Preparation of 3-aryl-isoxazol-5-yl benzoates

3-Aryl-isoxazol-5-yl benzoates are prepared by an acid catalyzed solvolysis of 3'-(Aryl)-spiro[isobenzofuran-1(3H),5'(4'H)-isoxazol]-3-one.