6908-41-4Relevant articles and documents
Ambient-pressure highly active hydrogenation of ketones and aldehydes catalyzed by a metal-ligand bifunctional iridium catalyst under base-free conditions in water
Wang, Rongzhou,Yue, Yuancheng,Qi, Jipeng,Liu, Shiyuan,Song, Ao,Zhuo, Shuping,Xing, Ling-Bao
, p. 1 - 7 (2021/05/17)
A green, efficient, and high active catalytic system for the hydrogenation of ketones and aldehydes to produce corresponding alcohols under atmospheric-pressure H2 gas and ambient temperature conditions was developed by a water-soluble metal–ligand bifunctional catalyst [Cp*Ir(2,2′-bpyO)(OH)][Na] in water without addition of a base. The catalyst exhibited high activity for the hydrogenation of ketones and aldehydes. Furthermore, it was worth noting that many readily reducible or labile functional groups in the same molecule, such as cyan, nitro, and ester groups, remained unchanged. Interestingly, the unsaturated aldehydes can be also selectively hydrogenated to give corresponding unsaturated alcohols with remaining C=C bond in good yields. In addition, this reaction could be extended to gram levels and has a large potential of wide application in future industrial.
Method for synthesizing primary alcohol in water phase
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Paragraph 0035-0036, (2021/07/14)
The invention discloses a method for synthesizing primary alcohol in a water phase. The method comprises the following steps: taking aldehyde as a raw material, selecting water as a solvent, and carrying out catalytic hydrogenation reaction on the aldehyde in the presence of a water-soluble catalyst to obtain the primary alcohol, wherein the catalyst is a metal iridium complex [Cp*Ir(2,2'-bpyO)(OH)][Na]. Water is used as the solvent, so that the use of an organic solvent is avoided, and the method is more environment-friendly; the reaction is carried out at relatively low temperature and normal pressure, and the reaction conditions are mild; alkali is not needed in the reaction, so that generation of byproducts is avoided; and the conversion rate of the raw materials is high, and the yield of the obtained product is high. The method not only has academic research value, but also has a certain industrialization prospect.
Ruthenium(II) Complex of a Tridentate Azoaromatic Pincer Ligand and its Use in Catalytic Transfer Hydrogenation of Aldehydes and Ketones with Isopropanol
Saha, Tanushri,Prasad Rath, Santi,Goswami, Sreebrata
, p. 1455 - 1461 (2021/05/18)
In this work, a new Ru(II) complex with the redox-active pincer 2,6-bis(phenylazo)pyridine ligand (L) is reported which acts as a metal-ligand bifunctional catalyst for transfer hydrogenation reactions. The isolated complex [(L)Ru(PMe2Ph)2(CH3CN)](ClO4)2; [1](ClO4)2 is characterized by a host of spectroscopic measurements and X-ray structure determination. It is diamagnetic and single-crystal X-ray structure analysis reveals that [1]2+ adopts a distorted octahedral geometry where L binds Ru center in meridional fashion. The observed elongation in the coordinated azo bond length (1.29 ?) is attributed to the extensive π-back bonding, dπ(RuII)→π*(azo)L. The complex [1](ClO4)2 acts as an efficient catalyst, which brings about catalytic transfer hydrogenation reactions of a broad array of aldehydes and ketones in isopropanol and in inert conditions. The selectivity of the catalyst for aldehyde reduction over the other reducible functional groups such as nitro, nitrile, ester etc was also investigated. Mechanistic studies, examined by suitable control reactions and isotope labelling experiments, indicate synergistic participation of both ligand and metal centres via the formation of a fleeting Ru?H intermediate and hydrogen walking to the coordinated azo function of L.
