69116-22-9

Basic information

• Product Name: Benzene, 1-(iodoethynyl)-4-nitro-
• CAS NO: 69116-22-9
• Molecular Formula: C8H4INO2
• Molecular Weight: 273.03
• Mol File: 69116-22-9.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(iodoethynyl)-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(iodoethynyl)-4-nitro-(69116-22-9)
• EPA Substance Registry System: Benzene, 1-(iodoethynyl)-4-nitro-(69116-22-9)

Safety Data

• Hazardous Substances Data: 69116-22-9(Hazardous Substances Data)

Upstream product

• 937-31-5 (4-Nitrophenyl)acetylene 
• 48129-93-7 1-copper(I) (4-nitrophenyl)ethyne 
• 69116-23-0 C₁₈H₁₅OP*C₈H₄INO₂ 
• 77271-12-6 C₁₈H₁₅AsO*C₈H₄INO₂ 
• 940-13-6 1-(2-bromoethynyl)-4-nitrobenzene 
• 636-98-6 p-nitrobenzene iodide 
• 75867-38-8 4-nitro-1-(trimethylsilylethynyl)benzene 
• 75-47-8 iodoform 
• 555-16-8 4-nitrobenzaldehdye 
• 586-78-7 para-nitrophenyl bromide 

Downstream Products

• 1361582-91-3 N-(3-bromobut-3-en-1-yl)-4-methyl-N-((4-nitrophenyl)ethynyl)benzenesulfonamide 
• 491593-81-8 1-(3,3-difluoro-2-iodo-cycloprop-1-enyl)-4-nitro-benzene 
• 1942-30-9 4-(phenylethynyl)nitrobenzene 
• 39082-40-1 1-[2-(4-methoxyphenyl)ethynyl]-4-nitrobenzene 

Relevant articles and documents

Halo-1,2,3-triazolium salts as halogen bond donors for the activation of imines in dihydropyridinone synthesis

In the past decade halogen bond (XB) catalysis has gained considerable attention. Halo-triazoles are known XB donors, yet few examples detail their use as catalysts. As a continuation of our previous work the catalytic properties of substituted enantiomerically pure halo-triazolium salts were explored in the reaction between an imine and Danishefsky's diene leading to the formation of dihydropyridinone. The catalytic activity of the XB donors was highly dependent on the choice of the halogen atom and on the counterion. Also, it was found that impurities in the diene affected the rate of the reaction.

Activation of Michael Acceptors by Halogen-Bond Donors

Extending earlier studies on iodine catalysis, experimental investigations show that various halogen-bond donors can also be employed to accelerate the Michael addition between trans -crotonophenone and indole. Solvent as well as counteranion effects have been analyzed, and kinetic and computational investigations provide additional insights into the mode of activation.

A Base-Free Multicomponent Domino Approach: One-Pot Synthesis of 2-Iminothiazolines via Oxy-Iodination of Arylacetylenes

A simple and an efficient multicomponent domino protocol is developed for the synthesis of 2-iminothiazolines starting from simple and readily available arylacetylenes, amines, and phenyl isothiocyanates under base-free conditions. The present method invo