69120-06-5 Usage
Description
5-(6-Hydroxybenzofuran-2-yl)-2-(3-methyl-2-butenyl)-1,3-benzenediol is a complex organic compound characterized by its unique molecular structure. It is a type of benzenediol, which means it contains two hydroxyl (-OH) groups attached to a benzene ring. The presence of a benzofuran and a 3-methyl-2-butenyl group further distinguishes this compound and may contribute to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
5-(6-Hydroxybenzofuran-2-yl)-2-(3-methyl-2-butenyl)-1,3-benzenediol is used as a pharmaceutical compound for its potential therapeutic properties. 5-(6-Hydroxybenzofuran-2-yl)-2-(3-methyl-2-butenyl)-1,3-benzenediol's unique structure may allow it to interact with specific biological targets, making it a candidate for the development of new drugs.
Used in Drug Development:
In the field of drug development, 5-(6-Hydroxybenzofuran-2-yl)-2-(3-methyl-2-butenyl)-1,3-benzenediol is utilized as a starting material or a key intermediate in the synthesis of various pharmaceutical agents. Its chemical versatility and the presence of multiple functional groups make it a valuable component in the creation of novel drug molecules.
Used in Antimicrobial Applications:
5-(6-Hydroxybenzofuran-2-yl)-2-(3-methyl-2-butenyl)-1,3-benzenediol is used as an antimicrobial agent, particularly against Staphylococcus aureus. It acts as an inhibitor of enoyl-acyl carrier protein reductase, a key enzyme involved in bacterial fatty acid synthesis, thereby disrupting the bacterial cell membrane and inhibiting its growth.
Used in Diabetes Treatment:
Moracin C, a compound related to 5-(6-Hydroxybenzofuran-2-yl)-2-(3-methyl-2-butenyl)-1,3-benzenediol, is used as a diabetic medication. It may also be utilized in the development of other drugs due to its potential therapeutic effects on glucose metabolism and insulin sensitivity.
Check Digit Verification of cas no
The CAS Registry Mumber 69120-06-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,1,2 and 0 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 69120-06:
(7*6)+(6*9)+(5*1)+(4*2)+(3*0)+(2*0)+(1*6)=115
115 % 10 = 5
So 69120-06-5 is a valid CAS Registry Number.
InChI:InChI=1/C19H18O4/c1-11(2)3-6-15-16(21)7-13(8-17(15)22)18-9-12-4-5-14(20)10-19(12)23-18/h3-5,7-10,20-22H,6H2,1-2H3
69120-06-5Relevant articles and documents
Synthesis of moracin C and its derivatives with a 2-arylbenzofuran motif and evaluation of their PCSK9 inhibitory effects in HepG2 cells
BasavanaGowda, Melanayakanakatte Kuberappa,Chae, Hee-Sung,Choi, Won Jun,Masagalli, Jagadeesh Nagarajappa
, (2021/05/31)
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key factor in several cardiovascular diseases, as it is responsible for the elevation of circulating low-density lipoprotein cholesterol (LDL-C) levels in blood plasma by direct interaction with t
Total synthesis of moracin C
McAllister, Graeme D.,Hartley, Richard C.,Dawson, Michael J.,Knaggs, Andrew R.
, p. 3453 - 3457 (2007/10/03)
Moracin C has been synthesised by the most efficient route to date (10 steps and 12% overall yield). The relatively unexplored acid-induced, intramolecular migration of an acyl group from an ortho phenolic hydroxy to a benzylic hydroxy is used to synthesise o-hydroxybenzylphosphonium salts containing ester groups. The phosphonium salts are coupled with 3,5-dimethoxybenzoic acid. Intramolecular Wittig reaction then gives 2-arylbenzo[b]furans, bearing the key 1′,3′,5′ substitution pattern on the aryl ring. This discovery provides a concise route to polyphenolic benzo[b]furans that we expect to be of general utility.
