691407-33-7Relevant articles and documents
Synthesis of (2S,3S)-3′-fluoroisoleucine
Charrier, Jean-Damien,Hadfield, David S.,Hitchcock, Peter B.,Young, Douglas W.
, p. 797 - 802 (2007/10/03)
The fluorinated amino acid, (2S,3S)-3′-fluoroisoleucine, 3, has been synthesised by a route involving stereoselective cuprate or photochemical addition to the compound 4, derived in turn from (2S)-pyroglutamic acid. This provides a reporter group for the hydrophobic amino acid (2S)-isoleucine for use in protein studies.