691841-17-5

Basic information

• Product Name: 1-benzylamino-3-[4-(2-methoxy-ethyl)-phenoxy]-propan-2-ol
• CAS NO: 691841-17-5
• Molecular Weight: 315.412
• Mol File: 691841-17-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzylamino-3-[4-(2-methoxy-ethyl)-phenoxy]-propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzylamino-3-[4-(2-methoxy-ethyl)-phenoxy]-propan-2-ol(691841-17-5)
• EPA Substance Registry System: 1-benzylamino-3-[4-(2-methoxy-ethyl)-phenoxy]-propan-2-ol(691841-17-5)

Safety Data

• Hazardous Substances Data: 691841-17-5(Hazardous Substances Data)

Upstream product

• 56718-71-9 4-(2-methoxyethyl)phenol 
• 56718-70-8 2-[4-(2'-methoxyethyl)phenoxymethyl]oxirane 
• 100-46-9 benzylamine 

Relevant articles and documents

Design, synthesis and evaluation of racemic 1-(4-hydroxyphenyl)-2-[3- (substituted phenoxy)-2-hydroxy-1-propyl]amino-1-propanol hydrochlorides as novel uterine relaxants

Novel 1-(4-hydroxyphenyl)-2-[3-(substituted phenoxy)-2-hydroxy-1-propyl] amino-1-propanol hydrochlorides were designed based on the pharmacophore for potent uterine relaxant activity and by utilizing the principles of structural hybridization. The designed molecules were synthesized as racemates by a novel route and were evaluated for uterine relaxant activity in vitro on isolated rat uterus and in vivo in pregnant rats. Their cAMP-releasing potential was studied using rat uterus tissue homogenates by the cAMP [3H] assay, and cardiac stimulant potential was evaluated on isolated guinea pig right atrium. All compounds exhibited potent uterine relaxant activity in vitro and produced a significant delay in the onset of labour in pregnant rats; their cAMP-releasing potential was slightly less, while their cardiac stimulant potential was insignificant as compared to isoxsuprine hydrochloride.