691862-64-3

Basic information

• Product Name: 1-(3-fluoro-phenyl)-1H-pyrrole-3-carbaldehyde
• CAS NO: 691862-64-3
• Molecular Weight: 189.189
• Mol File: 691862-64-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3-fluoro-phenyl)-1H-pyrrole-3-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-fluoro-phenyl)-1H-pyrrole-3-carbaldehyde(691862-64-3)
• EPA Substance Registry System: 1-(3-fluoro-phenyl)-1H-pyrrole-3-carbaldehyde(691862-64-3)

Safety Data

• Hazardous Substances Data: 691862-64-3(Hazardous Substances Data)

Upstream product

• 50634-05-4 2,5-dimethoxy-3-tetrahydrofurancarboxaldehyde 
• 372-19-0 meta-fluoroaniline 

Downstream Products

• 691863-08-8 methanesulfonic acid 3-[1-(3-fluoro-phenyl)-1H-pyrrol-3-yl]-2-oxo-oxazolidin-5-ylmethyl ester 
• 691863-20-4 5-azidomethyl-3-[1-(3-fluoro-phenyl)-1H-pyrrol-3-yl]-oxazolidin-2-one 
• 691862-84-7 [1-(3-fluoro-phenyl)-1H-pyrrol-3-yl]-carbamic acid benzyl ester 
• 691863-32-8 5-aminomethyl-3-[1-(3-fluoro-phenyl)-1H-pyrrol-3-yl]-oxazolidin-2-one 
• 691862-96-1 3-[1-(3-fluoro-phenyl)-1H-pyrrol-3-yl]-5-hydroxymethyl-oxazolidin-2-one 
• 691862-74-5 1-(3-fluoro-phenyl)-1H-pyrrole-3-carboxylic acid 

Relevant articles and documents

Novel HIV-1 protease inhibitors active against multiple PI-Resistant viral strains: Coadministration with indinavir

HIV-1 protease inhibitors (PI) with an N-arylpyrrole moiety in the P 3 position afforded excellent antiviral potency and substantially improved aqueous solubility over previously reported variants. The rapid in vitro clearance of these compounds in human liver microsomes prompted oral coadministration with indinavir to hinder their metabolism by the cyctochrome P450 3A4 isozyme and allow for in vivo PK assessment.