691871-71-3

Basic information

• Product Name: (6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-benzyl-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
• CAS NO: 691871-71-3
• Molecular Weight: 465.508
• Mol File: 691871-71-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-benzyl-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-benzyl-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione(691871-71-3)
• EPA Substance Registry System: (6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-benzyl-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione(691871-71-3)

Safety Data

• Hazardous Substances Data: 691871-71-3(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 171489-59-1 methyl (1R,3R)-1-(3,4-methylenedioxyphenyl)-2-chloroacetyl-2,3,4,9-tetrahydro-9H-pyrido[3,4-b]indol-3-carboxylate 
• 171596-41-1 (1R,3R)-methyl 1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate 
• 14907-27-8 (R)-(+)-tryptophan methyl ester hydrochloride 
• 120-57-0 piperonal 

Relevant articles and documents

Synthesis and SAR of tetracyclic pyrroloquinolones as phosphodiesterase 5 inhibitors

The synthesis of the fused tetracyclic pyrroloquinolones 9a-i in four steps is described. The PDE5 inhibitory activities of these compounds, their selectivities against PDE1, PDE2, PDE3, PDE4 and PDE6, the preclinical pharmacokinetic assessments and the in vivo efficacy in increasing intracavernosal pressure are presented and discussed.