69207-44-9

Basic information

• Product Name: 4-CHLORO-2-METHYLPYRIDAZIN-3(2H)-ONE
• Synonyms: 4-CHLORO-2-METHYLPYRIDAZIN-3(2H)-ONE
• CAS NO: 69207-44-9
• Molecular Formula: C₅H₅ClN₂O
• Molecular Weight: 144.559
• Mol File: 69207-44-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 196.7°C at 760 mmHg
• Flash Point: 72.8°C
• Appearance: /
• Density: 1.37g/cm³
• Vapor Pressure: 0.393mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: 4-CHLORO-2-METHYLPYRIDAZIN-3(2H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-2-METHYLPYRIDAZIN-3(2H)-ONE(69207-44-9)
• EPA Substance Registry System: 4-CHLORO-2-METHYLPYRIDAZIN-3(2H)-ONE(69207-44-9)

Safety Data

• Hazardous Substances Data: 69207-44-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H5ClN2O/c1-8-5(9)4(6)2-3-7-8/h2-3H,1H3

Upstream product

• 933-76-6 4,5-dichloro-2-methyl-3(2H)-pyridazinone 
• 1075-08-7 4-Chloro-5-hydrazino-2-methyl-3(2H)-pyridazinone 
• 1677-79-8 4-chloropyridazin-3-ol 
• 74-88-4 methyl iodide 
• 1677-79-8 4-chloro-2,3-dihydropyridazin-3-one 

Downstream Products

• 98700-55-1 4-<(3-tert-Butyl-2-phenyl-1,3-oxazolidin-5-yl)methoxy>-2-methylpyridazin-3(2H)-one 
• 874955-65-4 2-methyl-4-(2-pivaloylaminophenyl)pyridazin-3(2H)-one 
• 874955-66-5 4-(2-aminophenyl)-2-methylpyridazin-3(2H)-one 

Relevant articles and documents

IMIDAZO[1,2-C]PYRIMIDINE DERIVATIVES AS PRC2 INHIBITORS FOR TREATING CANCER

Disclosed are compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, disclosed are compounds of Formula (I) and pharmaceutical compositions thereof, and methods of using the compounds and pharmaceutical compositions in, for example, methods of treating cancer.

PRC2 INHIBITORS

The present invention relates to compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention. (Formula (I))