6926-49-4

Basic information

• Product Name: 5-[4-(2H-tetrazol-5-yl)phenyl]-2H-tetrazole
• Synonyms: 5-[4-(2H-tetrazol-5-yl)phenyl]-2H-tetrazole
• CAS NO: 6926-49-4
• Molecular Formula: C₈H₆N₈
• Molecular Weight: 214.18684
• EINECS: -0
• Mol File: 6926-49-4.mol
• Article Data: 28

Chemical Properties

• Melting Point: 296-297 °C (decomp)
• Boiling Point: 539.1°Cat760mmHg
• Flash Point: 269.5°C
• Appearance: /
• Density: 1.575g/cm³
• PKA: 3.63±0.10(Predicted)
• CAS DataBase Reference: 5-[4-(2H-tetrazol-5-yl)phenyl]-2H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[4-(2H-tetrazol-5-yl)phenyl]-2H-tetrazole(6926-49-4)
• EPA Substance Registry System: 5-[4-(2H-tetrazol-5-yl)phenyl]-2H-tetrazole(6926-49-4)

Safety Data

• Hazardous Substances Data: 6926-49-4(Hazardous Substances Data)

Usage

General Description

5-[4-(2H-tetrazol-5-yl)phenyl]-2H-tetrazole is a chemical compound with a molecular formula of C8H6N10. It is a tetrazole derivative that contains two tetrazole rings and a phenyl group. Tetrazoles are a class of organic compounds that contain a five-membered ring with four nitrogen atoms and are known for their diverse range of biological and pharmacological activities. This particular compound may have potential applications in pharmaceuticals as a building block for synthesizing new drugs or as a ligand in coordination chemistry due to its unique structure and properties. However, further research and testing would be necessary to determine its specific uses and properties.

Upstream product

• 623-26-7 terephthalonitrile 
• 106-37-6 1.4-dibromobenzene 
• 623-27-8 terephthalaldehyde, 
• 52707-54-7 4-cyanobenzaldehyde oxime 
• 624-38-4 para-diiodobenzene 
• 14389-10-7 5-(4-cyanophenyl)-2H-tetrazole 
• 176636-08-1 2,2'-bis(tributylstannyl)-5,5'-p-phenylenebis(tetrazole) 

Downstream Products

• 100137-06-2 5,5'-dimethyl-2,2'-p-phenylene-bis-[1,3,4]oxadiazole 
• 103569-13-7 4,4'-(5,5'-p-phenylene-bis-[1,3,4]oxadiazol-2-yl)-bis-benzonitrile 
• 22915-82-8 5,5'-di(4-nitrophenyl)-1,4-phenylenebis-1,3,4-oxadiazole 
• 100-42-5 styrene 
• 95-47-6 o-xylene 
• 106-42-3 para-xylene 
• 108-38-3 m-xylene 
• 536-74-3 phenylacetylene 
• 108-88-3 toluene 
• 307298-06-2 1,4-phenylene-5,5'-bis(2-tert-butyltetrazole) 
• 127612-19-5 1,4-di<5-(2-furyl)-1,3,4-oxadiazol-2-yl>-benzene 
• 5888-97-1 5,5'-diphenyl-1,4-phenylenebis-1,3,4-oxadiazole 
• 66012-77-9 1,4-phenylene-5,5'-bis(1-methyltetrazole) 
• 119722-37-1 1⁽²⁾H,1'(2')H-5,5'-[4,4'-(5,5'-p-phenylene-bis-[1,3,4]oxadiazol-2-yl)-diphenyl]-bis-tetrazole 

Relevant articles and documents

Tetrazoles: A new class of compound for crystallization modification

Tetrazoles are a class of organic compound often used as carboxylic acid analogues. This analogous behaviour is shown to extend to crystallization modification, that is, tetrazoles are also able to influence crystal growth and morphology although in a dif

CuO–NiO bimetallic nanoparticles supported on graphitic carbon nitride with enhanced catalytic performance for the synthesis of 1,2,3-triazoles, bis-1,2,3-triazoles, and tetrazoles in parts per million level

The unification of CuCl2·2H2O and NiCl2·6H2O with the support of graphitic carbon nitride yielded to form an efficient, synergistic, bimetallic nano-catalyst CuO–NiO@g-C3N4. FT-IR, SEM, TEM

Synthesis, Biological Activity, and Molecular Docking Assessment of Some New Sulfonylated Tetrazole Derivatives

The designed molecular structures have been subjected to computational analysis for calculating their physicochemical properties and drug likeness. The calculated data indicate that most of the compound possess the bioactivity score in the active zone. Synthetic approach to the target compounds is straightforward and easy to handle. Structures of the new compounds are supported by FT-IR, 1H, and 13C NMR, and mass spectra. Antimicrobial tests of the products against pathogens (S. aureus, S. epidermidis, E. coli, and P. mirabilis) indicate the products as active or highly active. Their cyto-toxicity is determined to be 92–98% at concentration of 3.125 μmol/L. The molecular docking analysis carried out for the target compounds against the receptor Glc-N-6P exhibits low binding energy and various binding sites of those.

Dendron-functionalized Fe3O4 magnetic nanoparticles with palladium catalyzed CN insertion of arylhalide for the synthesis of tetrazoles and benzamide

A novel method for the one-pot synthesis of 5-substituted 1H-tetrazoles and Benzamide from arylhalide containing in situ CN insertion from inorganic salt source was accomplished in presence of a new magnetically catalyst, palladium on surface-modified Schiff-Base complex. K2[Ni(CN)4] plays a role of nontoxic inorganic cyanide source in arylhalide Nucleophilic substitution. The synthesized Pd-Schiff-Base@Fe3O4MNPs was characterized by various techniques such as FT-IR, TGA, SEM, VSM, XRD, TEM, ICP-AES, EDX, BET and XPS. The nano structure catalyst was easily recovered by external magnetic field and reused several times without noticeable loss of its catalytic activity. Leaching study of Pd-Schiff-Base@Fe3O4 MNPs shows palladium strong bonded to different active parts of catalyst surface. Heterogeneity of this catalyst has been examined using hot filtration and ICP-AES techniques.