69321-60-4

Basic information

• Product Name: 2,6-Dibromotoluene
• Synonyms: 1,3-Dibromo-2-methylbenzene;Benzene, 1,3-dibromo-2-methyl-;2,6-DIBROMOTOLUENE;2,6-Dibromotoluene, 98+%;2,6-Dibromotoluene, 98.5%
• CAS NO: 69321-60-4
• Molecular Formula: C₇H₆Br₂
• Molecular Weight: 249.93
• EINECS: 250-689-9
• Product Categories: Halogen toluene;Bromine Compounds
• Mol File: 69321-60-4.mol
• Article Data: 11

Chemical Properties

• Melting Point: 2-6°C
• Boiling Point: 112-113°C 7mm
• Flash Point: 112-113°C/7mm
• Appearance: /
• Density: 1,812 g/cm3
• Vapor Pressure: 0.0436mmHg at 25°C
• Refractive Index: 1.6060
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 3235502
• CAS DataBase Reference: 2,6-Dibromotoluene(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dibromotoluene(69321-60-4)
• EPA Substance Registry System: 2,6-Dibromotoluene(69321-60-4)

Safety Data

• Statements: 36/37/38-36/38
• Safety Statements: 26-36/37/39-37
• Hazardous Substances Data: 69321-60-4(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

Preparation

2,6-Dibromotoluene is an important pharmaceutical intermediate，It can be made from toluene using sulfonation and desulfonation as intermediate steps in the synthesis.

InChI:InChI=1/C7H6Br2/c1-5-6(8)3-2-4-7(5)9/h2-4H,1H3

Upstream product

• 55289-36-6 3-bromo-2-methylaniline 
• 13194-73-5 3,5-dibromo-4-methylaniline 
• 80948-78-3 2,4-dibromo-3-methylaniline 
• 108545-81-9 1,3-dibromo-5-tert-butyl-2-methylbenzene 
• 99-99-0 1-methyl-4-nitrobenzene 
• 101581-06-0 1,3-dibromo-2-methyl-5-nitrobenzene 
• 55289-35-5 2-bromo-6-nitrotoluene 
• 98-51-1 4-tert-butyltoluene 
• 4162-89-4 4-(tert-butyl)-2,6-dinitrotoluene 
• 98840-42-7 2,6-diamino-4-t-butyltoluene 
• 90914-81-1 4-bromo-3-methylacetanilide 
• 827-32-7 4-bromo-5-methyl-2-nitrophenylamine 
• 594-27-4 tetramethylstannane 
• 1177558-44-9 (3,5-dibromo-4-methylphenyl)amine hydrochloride 

Downstream Products

• 116779-85-2 2,3,6-tribromo-toluene 
• 67713-23-9 2,6-dibromobenzaldehyde 
• 93701-32-7 2,6-dibromobenzyl bromide 
• 110127-07-6 2,6-dibromo-3-nitro-toluene 
• 69321-59-1 (3-bromo-2-methyl-phenyl)-phenyl sulfone 
• 392318-87-5 2,6-dibromo-3,5-dinitro-toluene 
• 72443-64-2 N,N-Dimethyl-3-bromo-2-methylbenzylamine 
• 601-84-3 2,6-dibromobenzoic acid 
• 51689-50-0 2-methylbenzene-1,3-dicarboxaldehyde 
• 865756-45-2 2,6-bis(4-pyridylethynyl)toluene 
• 80515-60-2 2,6-dideuteriotoluene 
• 923282-14-8 [2,6-2H₂]benzyl bromide 
• 159618-36-7 2,6-Dicyanobenzaldehyde 
• 331714-62-6 2-(2,6-dibromophenyl)-1,3-dioxolane 

Relevant articles and documents

Through space interaction between ferrocenes mediated by a thioether

A series of conformationally constrained 2,6-bisferrocenylphenyl thioethers were synthesized via Suzuki-Miyaura cross coupling reactions. Structural information was obtained using X-ray crystallography and dynamic 1H NMR spectroscopic studies,

Dual Pharmacophores - PDE4-Muscarinic Antagonistics

The present invention is directed to novel compounds of Formula (I), pharmaceutical compositions and their use in therapy, for example as inhibitors of phosphodiesterase type IV (PDE4) and as antagonists of muscarinic acetylcholine receptors (mAChRs), in the treatment of/and or prophylaxis of respiratory diseases, including antiinflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.

DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS

The present invention is directed to novel compounds of Formula's (I) - (VI), and pharmaceutically acceptable salts thereof, pharmaceutical compositions and their use in therapy, for example as inhibitors of phosphodiesterase type IV (PDE4) and as antagonists of muscarinic acetylcholine receptors (mAChRs), in the treatment of and/or prophylaxis of respiratory diseases, including inflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.