69350-76-1

Basic information

• Product Name: methyl 2,3,5-tri-O-benzoyl-αβ-D-ribofuranoside
• Synonyms: methyl 2,3,5-tri-O-benzoyl-αβ-D-ribofuranoside
• CAS NO: 69350-76-1
• Molecular Weight: 476.483
• Mol File: 69350-76-1.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: methyl 2,3,5-tri-O-benzoyl-αβ-D-ribofuranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2,3,5-tri-O-benzoyl-αβ-D-ribofuranoside(69350-76-1)
• EPA Substance Registry System: methyl 2,3,5-tri-O-benzoyl-αβ-D-ribofuranoside(69350-76-1)

Safety Data

• Hazardous Substances Data: 69350-76-1(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 56607-40-0 methyl D-arabinofuranoside 
• 50-69-1 D-ribose 
• 37077-81-9 1,2-isopropylidene-α-D-ribofuranose 
• 63846-98-0 1,2-O-(1-Methylethylidene)-α-D-ribo-pentodialdo-1,4-furanose 
• 4495-04-9 1,2-O-isopropylidene-α-D-allofuranose 
• 2595-05-3 Diacetone D-glucose 
• 2847-00-9 1,2:5,6-di-O-isopropylidene-α-D-hexofuran-3-ulose 
• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 2280-44-6 D-Glucose 
• 162491-62-5 (2S,3R,4S)-2-(hydroxymethyl)-5-methoxyoxolane-3,4-diol 
• 532-20-7 D-Ribose 
• 1824-96-0 methyl ribofuranoside 
• 1824-96-0 Methyl α-lyxofuranoside 

Downstream Products

• 70051-90-0 tri-O-benzoyl-β-D-arabinofuranosyl bromide 
• 4348-68-9 2,3,5-tri-O-benzoyl-α-D-arabinofuranosyl bromide 
• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 
• 16205-60-0 2,3,5-tri-O-benzoyl-β-D-ribofuranosyl bromide 
• 146762-17-6 1-(2,3,5-Tri-O-benzoyl-α-D-arabinofuranosyl)-5-chlorouracil 
• 146762-19-8 1-(2,3,5-Tri-O-benzoyl-α-D-arabinofuranosyl)-5-(4-benzylpiperazino)uracil 
• 147909-83-9 6-Ethyl-1-(2,3,5-tri-O-benzoyl-α-D-arabinofuranosyl)uracil 
• 147909-88-4 6-Ethyl-3-(2,3,5-tri-O-benzoyl-α-D-arabinofuranosyl)-2-thiouracil 
• 147909-87-3 6-Methyl-3-(2,3,5-tri-O-benzoyl-α-D-arabinofuranosyl)-2-thiouracil 
• 80393-99-3 1-(2,3,5-Tri-O-benzoyl-α-D-arabinofuranosyl)-5-methyluracil 
• 147909-80-6 6-Methyl-1,3-bis(2,3,5-tri-O-benzoyl-α-D-arabinofuranosyl)uracil 

Relevant articles and documents

Application of nicotinamide riboside aromatic formate compound and composition thereof and compound crystal form

The invention provides application of a nicotinamide riboside triaryl formate compound and a composition thereof in improving the level of coenzyme I (NAD) in the human body, improving health conditions or treating related diseases, and a compound in a crystal form shown in the formula (II-1). The structure of the nicotinamide riboside triaryl formate compound is as shown in a formula (I). As a synthesis precursor of NAD, compared with nicotinamide nucleoside, the nicotinamide nucleoside triaryl formate compound not only can effectively improve the level of NAD in the human body, but also is easier to prepare, the cost is remarkably reduced, and the nicotinamide nucleoside triaryl formate compound has remarkable industrial application advantages.

3-Trifluoromethylpyrazolones derived nucleosides: Synthesis and antiviral evaluation

Dengue (DENV) viral infection is a global public health problem that infrequently develops life threatening diseases such as dengue hemorrhagic fever (DFS) and dengue shock syndrome (DSS). Middle East respiratory syndrome coronavirus (MERS-CoV) is a highly pathogenic human corona virus with 38% fatality rate of infected patients. A series of 4-arylhydrazono-5-trifluoromethyl-pyrazolones, their ribofuranosyl, and 5′-deoxyribofuranosyl nucleosides were synthesized, geometry optimized using Density functional theory (DFT), and evaluated for their antiviral activity. 2-Nitrophenylhydrazonopyra-zolone derivative 5 showed significant activity against MERS-CoV (EC50 = 4.6 μM). The nucleoside analog 8 showed moderate activity against DENV-2 (EC50 = 10 μM), while the activity was abolished with the corresponding 5′-deoxyribonucleoside analogs. The identified hits in this study set this category of compounds for further future optimizations.

Preparation of the tri-arabino di-mycolate fragment of mycobacterial arabinogalactan from defined synthetic mycolic acids

An efficient synthetic approach to tri-arabino di-mycolates, using structurally defined synthetic α-, keto and methoxy mycolic acids is described.