69385-30-4 Usage
Description
2,6-Difluorobenzylamine is an organic compound characterized by its clear colorless to yellow liquid appearance. It is a derivative of benzylamine with two fluorine atoms substituted at the 2nd and 6th positions on the benzene ring, which imparts unique chemical properties to the molecule.
Uses
Used in Pharmaceutical Industry:
2,6-Difluorobenzylamine is used as a synthetic intermediate for the development of various pharmaceutical compounds. Its unique chemical structure allows it to be a key component in the synthesis of complex molecules with potential therapeutic applications.
2,6-Difluorobenzylamine is used as a building block for the synthesis of (Z)-N1-(2,6-difluorobenzyl)-N2-(2-amino-1,2-dicyanovinyl)formamidine, a compound with potential applications in medicinal chemistry.
Additionally, 2,6-Difluorobenzylamine is utilized in the synthesis of 2,6-difluorobenzyl-guanidine hydrochloride, which may have uses in the development of new drugs targeting specific biological pathways.
Check Digit Verification of cas no
The CAS Registry Mumber 69385-30-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,3,8 and 5 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 69385-30:
(7*6)+(6*9)+(5*3)+(4*8)+(3*5)+(2*3)+(1*0)=164
164 % 10 = 4
So 69385-30-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H7F2N/c8-6-2-1-3-7(9)5(6)4-10/h1-3H,4,10H2/p+1
69385-30-4Relevant articles and documents
Gabriel reaction in the synthesis of 2,6-difluorobenzyl amine
Vasilevskaya, Tamara N.,Yakovleva, Olga D.,Kobrin, Victor S.
, p. 201 - 205 (1998)
2,6-Difluorobenzyl amine was obtained by Gabriel reaction with a good yield. Intermediate N-(2,6-difluorobenzyl) phthalimide was obtained in the presence of phase transfer catalysts.
SUBSTITUTED QUINAZOLINE DERIVATIVES AND THEIR USE AS INHIBITORS
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, (2008/06/13)
The use of a compound of formula (I) 1 or a salt, ester or amide thereof; where X is O, or S, S(O) or S(O)2, or NR6 where R6 is hydrogen or C1-6 alkyl,; R5 is an optionally substituted 5-membered heteroaromatic ring, R1, R2 ,R3, R4 are independently selected from various specified moieties, in the preparation of a medicament for use in the inhibition of aurora 2 kinase. Certain compounds are novel and these, together with pharmaceutical compositions containing them are also described and claimed
Novel benzylideneaminoguanidines
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, (2008/06/13)
This disclosure describes novel substituted benzylideneaminoguanidines useful as anti-hypertensive agents and as diuretics.
