6939-33-9

Basic information

• Product Name: 7-METHYL-1-NAPHTHOL
• Synonyms: 7-METHYL-1-NAPHTHOL;1-Hydroxy-7-methylnaphthalene;NSC 57009;7-Methyl-naphthalen-1-ol
• CAS NO: 6939-33-9
• Molecular Formula: C₁₁H₁₀O
• Molecular Weight: 158.2
• Mol File: 6939-33-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 110-111℃
• Boiling Point: 307.4°C at 760 mmHg
• Flash Point: 148.8°C
• Appearance: /
• Density: 1.144g/cm³
• Vapor Pressure: 0.0004mmHg at 25°C
• Refractive Index: 1.656
• PKA: 9.57±0.40(Predicted)
• CAS DataBase Reference: 7-METHYL-1-NAPHTHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 7-METHYL-1-NAPHTHOL(6939-33-9)
• EPA Substance Registry System: 7-METHYL-1-NAPHTHOL(6939-33-9)

Safety Data

• Hazardous Substances Data: 6939-33-9(Hazardous Substances Data)

Usage

General Description

7-Methyl-1-naphthol, also known as 7-methyl-1-naphthalenol, is a chemical compound with the molecular formula C11H10O. It is a white to off-white solid that is insoluble in water but soluble in organic solvents. 7-Methyl-1-naphthol is often used as an intermediate in the synthesis of dyes, pigments, and pharmaceuticals. It is also used as a reagent in organic chemical reactions and as a fluorescent probe in analytical and biological studies. Additionally, it has been found to exhibit antioxidant and anti-inflammatory properties, making it a potentially useful compound for medicinal and cosmetic applications. However, 7-Methyl-1-naphthol should be handled with care, as it may be harmful if ingested, inhaled, or absorbed through the skin, and can cause irritation to the respiratory tract and skin.

InChI:InChI=1/C11H10O/c1-8-5-6-9-3-2-4-11(12)10(9)7-8/h2-7,12H,1H3

Upstream product

• 104115-64-2 2-bromo-7-methyl-1,2,3,4-tetrahydronapthalin-1-one 
• 121-69-7 N,N-dimethyl-aniline 
• 88-14-2 2-furanoic acid 
• 90500-13-3 5-methyl-2-iodosylbenzoic acid 
• 19061-31-5 1,4-dihydro-1,4-epoxy-6-methylnaphthalene 
• 127926-10-7 (+)-cis-1,2-dihydro-(1R,2S)-dihydroxy-7-methylnaphthalene 
• 91-57-6 2-Methylnaphthalene 

Downstream Products

• 6939-34-0 7-methyl-[1]naphthylamine 
• 6939-38-4 N-(7-methyl-[1]naphthyl)-acetamide 

Relevant articles and documents

Substituent-induced regioselective hydroxylation of the aromatic C-H bond on naphthalene with metachloroperbenzoic acid catalyzed by F20TPPMnCl

The regioselective hydroxylation of the aromatic C-H bond on a series of naphthalenes with different β-substituent R (R = H, Me, Et, i-Pr, OMe, COOH, Br, etc.) was studied, and the substituent effect on the regioselectivity was investigated. The electron-donating substituent afforded the aromatic C-H bond hydroxylation at the 1α position with more than 80% selectivity, while the electron-withdrawing substituent afforded the aromatic C-H bond hydroxylation at the 4α position with more than 60% selectivity of β-substituted naphthalene hydroxylated with metachloroperbenzoic acid catalyzed by tetrakis(pentafluorophenyl)porphyrin manganese(III) chloride. The research showed that the steric and electronic effects of the substituent appeared to play a significant role in determining the regioselectivity, and the electronic effect was of more importance than the steric effect of the substituent in the current situation. The studies may provide additional proofs for the stepwise mechanism of the aromatic C-H bond hydroxylation through a cationic intermediate. Copyright

ARYNIC SPECIES II; TOSYL AND TRIAZENE AS LEAVING GROUP IN THE GENERATION OF ARYNES FROM POLYMER-BOUND REAGENTS

o-Benzyne and its 4-methyl, 4-chloro and 4-bromo-derivatives were generated in the thermal decomposition of two new kinds of polymer-bound precursors: 1(2-carboxyaryl)triazenes and 2-carboxyaryl-sulphonates.New kinds of trapping polymers for these elusive

GENERATION OF MONOSUBSTITUTED o-BENZYNES FROM POLYMERIC REAGENTS VIA HETEROLYTIC FRAGMENTATIONS

Generation of four 4-substituted o-benzynes by heterolytic fragmentation reactions is demonstrated.